Becker JW - Search Results

1

FK-506-binding protein: three-dimensional structure of the complex with the antagonist L-685,818.

Becker JW, Rotonda J, McKeever BM, Chan HK, Marcy AI, Wiederrecht G, Hermes JD, Springer JP. Becker JW, et al. J Biol Chem. 1993 May 25;268(15):11335-9. J Biol Chem. 1993. PMID: 7684380 Free article.

2

Improved calcineurin inhibition by yeast FKBP12-drug complexes. Crystallographic and functional analysis.

Rotonda J, Burbaum JJ, Chan HK, Marcy AI, Becker JW. Rotonda J, et al. Among authors: becker jw. J Biol Chem. 1993 Apr 15;268(11):7607-9. doi: 10.2210/pdb1yat/pdb. J Biol Chem. 1993. PMID: 7681823 Free article.

3

Stromelysin-1: three-dimensional structure of the inhibited catalytic domain and of the C-truncated proenzyme.

Becker JW, Marcy AI, Rokosz LL, Axel MG, Burbaum JJ, Fitzgerald PM, Cameron PM, Esser CK, Hagmann WK, Hermes JD, et al. Becker JW, et al. Protein Sci. 1995 Oct;4(10):1966-76. doi: 10.1002/pro.5560041002. Protein Sci. 1995. PMID: 8535233 Free PMC article.

4

32-Indolyl ether derivatives of ascomycin: three-dimensional structures of complexes with FK506-binding protein.

Becker JW, Rotonda J, Cryan JG, Martin M, Parsons WH, Sinclair PJ, Wiederrecht G, Wong F. Becker JW, et al. J Med Chem. 1999 Jul 29;42(15):2798-804. doi: 10.1021/jm9806042. J Med Chem. 1999. PMID: 10425089

5

The three-dimensional structure of human granzyme B compared to caspase-3, key mediators of cell death with cleavage specificity for aspartic acid in P1.

Rotonda J, Garcia-Calvo M, Bull HG, Geissler WM, McKeever BM, Willoughby CA, Thornberry NA, Becker JW. Rotonda J, et al. Among authors: becker jw. Chem Biol. 2001 Apr;8(4):357-68. doi: 10.1016/s1074-5521(01)00018-7. Chem Biol. 2001. PMID: 11325591

6

Crystal structure of inhibitor-bound human 5-lipoxygenase-activating protein.

Ferguson AD, McKeever BM, Xu S, Wisniewski D, Miller DK, Yamin TT, Spencer RH, Chu L, Ujjainwalla F, Cunningham BR, Evans JF, Becker JW. Ferguson AD, et al. Among authors: becker jw. Science. 2007 Jul 27;317(5837):510-2. doi: 10.1126/science.1144346. Epub 2007 Jun 28. Science. 2007. PMID: 17600184

7

The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis.

Rotonda J, Nicholson DW, Fazil KM, Gallant M, Gareau Y, Labelle M, Peterson EP, Rasper DM, Ruel R, Vaillancourt JP, Thornberry NA, Becker JW. Rotonda J, et al. Among authors: becker jw. Nat Struct Biol. 1996 Jul;3(7):619-25. doi: 10.1038/nsb0796-619. Nat Struct Biol. 1996. PMID: 8673606

8

Comparison of the structure of human recombinant short form stromelysin by multidimensional heteronuclear NMR and X-ray crystallography.

Gooley PR, O'Connell JF, Marcy AI, Cuca GC, Axel MG, Caldwell CG, Hagmann WK, Becker JW. Gooley PR, et al. Among authors: becker jw. J Biomol NMR. 1996 Jan;7(1):8-28. doi: 10.1007/BF00190453. J Biomol NMR. 1996. PMID: 8720828

9

A combinatorial approach for determining protease specificities: application to interleukin-1beta converting enzyme (ICE).

Rano TA, Timkey T, Peterson EP, Rotonda J, Nicholson DW, Becker JW, Chapman KT, Thornberry NA. Rano TA, et al. Among authors: becker jw. Chem Biol. 1997 Feb;4(2):149-55. doi: 10.1016/s1074-5521(97)90258-1. Chem Biol. 1997. PMID: 9190289

10

Inhibition of stromelysin-1 (MMP-3) by P1'-biphenylylethyl carboxyalkyl dipeptides.

Esser CK, Bugianesi RL, Caldwell CG, Chapman KT, Durette PL, Girotra NN, Kopka IE, Lanza TJ, Levorse DA, MacCoss M, Owens KA, Ponpipom MM, Simeone JP, Harrison RK, Niedzwiecki L, Becker JW, Marcy AI, Axel MG, Christen AJ, McDonnell J, Moore VL, Olszewski JM, Saphos C, Visco DM, Hagmann WK, et al. Esser CK, et al. Among authors: becker jw. J Med Chem. 1997 Mar 14;40(6):1026-40. doi: 10.1021/jm960465t. J Med Chem. 1997. PMID: 9083493

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