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Page 1
UNCAN.eu: Toward a European Federated Cancer Research Data Hub.
Boutros M, Baumann M, Bigas A, Chaabane L, Guérin J, Habermann JK, Jobard A, Pelicci PG, Stegle O, Tonon G, Valencia A, Winkler EC, Blanc P, De Maria R, Medema RH, Nagy P, Tabernero J, Solary E. Boutros M, et al. Among authors: bigas a. Cancer Discov. 2024 Jan 12;14(1):30-35. doi: 10.1158/2159-8290.CD-23-1111. Cancer Discov. 2024. PMID: 38213296 Free PMC article.
β-Catenin activity induces an RNA biosynthesis program promoting therapy resistance in T-cell acute lymphoblastic leukemia.
García-Hernández V, Arambilet D, Guillén Y, Lobo-Jarne T, Maqueda M, Gekas C, González J, Iglesias A, Vega-García N, Sentís I, Trincado JL, Márquez-López I, Heyn H, Camós M, Espinosa L, Bigas A. García-Hernández V, et al. Among authors: bigas a. EMBO Mol Med. 2023 Feb 8;15(2):e16554. doi: 10.15252/emmm.202216554. Epub 2023 Jan 4. EMBO Mol Med. 2023. PMID: 36597789 Free PMC article.
IκBα controls dormancy in hematopoietic stem cells via retinoic acid during embryonic development.
Thambyrajah R, Maqueda M, Fadlullah MZ, Proffitt M, Neo WH, Guillén Y, Casado-Pelaez M, Herrero-Molinero P, Brujas C, Castelluccio N, González J, Iglesias A, Marruecos L, Ruiz-Herguido C, Esteller M, Mereu E, Lacaud G, Espinosa L, Bigas A. Thambyrajah R, et al. Among authors: bigas a. Nat Commun. 2024 Jun 1;15(1):4673. doi: 10.1038/s41467-024-48854-5. Nat Commun. 2024. PMID: 38824124 Free PMC article.
Loss of the epithelial marker CDX1 predicts poor prognosis in early-stage CRC patients.
Solé L, Lobo-Jarne T, Cabré-Romans JJ, González A, Fernández L, Marruecos L, Guix M, Cuatrecasas M, López S, Bellosillo B, Torres F, Iglesias M, Bigas A, Espinosa L. Solé L, et al. Among authors: bigas a. Biochim Biophys Acta Mol Cell Res. 2024 Mar;1871(3):119658. doi: 10.1016/j.bbamcr.2024.119658. Epub 2024 Jan 10. Biochim Biophys Acta Mol Cell Res. 2024. PMID: 38216091 Free article.
Genomics improves risk stratification of adults with T-cell acute lymphoblastic leukemia enrolled in measurable residual disease-oriented trials.
González-Gil C, Morgades M, Lopes T, Fuster-Tormo F, García-Chica J, Zhao R, Montesinos P, Torrent A, Diaz-Beya M, Coll R, Hermosín L, Mercadal S, González-Campos J, Zamora L, Artola T, Vall-Llovera F, Tormo M, Gil-Cortés C, Barba P, Novo A, Ribera J, Bernal T, De Ugarriza PL, Queipo MP, Martínez-Sánchez P, Giménez A, González-Martínez T, Cladera A, Cervera J, Fernández-Martín R, Ardaiz MÁ, Vidal MJ, Baena Á, López-Bigas N, Bigas A, Maciejewski J, Orfao A, Ribera JM, Genescà E. González-Gil C, et al. Among authors: bigas a. Haematologica. 2023 Apr 1;108(4):969-980. doi: 10.3324/haematol.2022.281196. Haematologica. 2023. PMID: 36325893 Free PMC article.
Abrogation of stemness in osteosarcoma by the mithramycin analog EC-8042 is mediated by its ability to inhibit NOTCH-1 signaling.
Estupiñán Ó, Rey V, Tornín J, Murillo D, Gallego B, Huergo C, Blanco-Lorenzo V, Victoria González M, Rodríguez A, Moris F, González J, Ayllón V, Ramos-Mejía V, Bigas A, Rodríguez R. Estupiñán Ó, et al. Among authors: bigas a. Biomed Pharmacother. 2023 Jun;162:114627. doi: 10.1016/j.biopha.2023.114627. Epub 2023 Apr 3. Biomed Pharmacother. 2023. PMID: 37018985 Free article.
IκB kinase-α coordinates BRD4 and JAK/STAT signaling to subvert DNA damage-based anticancer therapy.
Pecharromán I, Solé L, Álvarez-Villanueva D, Lobo-Jarne T, Alonso-Marañón J, Bertran J, Guillén Y, Montoto Á, Martínez-Iniesta M, García-Hernández V, Giménez G, Salazar R, Santos C, Garrido M, Borràs E, Sabidó E, Bonfill-Teixidor E, Iurlaro R, Seoane J, Villanueva A, Iglesias M, Bigas A, Espinosa L. Pecharromán I, et al. Among authors: bigas a. EMBO J. 2023 Nov 2;42(21):e114719. doi: 10.15252/embj.2023114719. Epub 2023 Sep 22. EMBO J. 2023. PMID: 37737566 Free PMC article.
SpadaHC: a database to improve the classification of variants in hereditary cancer genes in the Spanish population.
Moreno-Cabrera JM, Feliubadaló L, Pineda M, Prada-Dacasa P, Ramos-Muntada M, Del Valle J, Brunet J, Gel B, Currás-Freixes M, Calsina B, Salazar-Hidalgo ME, Rodríguez-Balada M, Roig B, Fernández-Castillejo S, Durán Domínguez M, Arranz Ledo M, Infante Sanz M, Castillejo A, Dámaso E, Soto JL, de Miguel M, Hidalgo Calero B, Sánchez-Zapardiel JM, Ramon Y Cajal T, Lasa A, Gisbert-Beamud A, López-Novo A, Ruiz-Ponte C, Potrony M, Álvarez-Mora MI, Osorio A, Lorda-Sánchez I, Robledo M, Cascón A, Ruiz A, Spataro N, Hernan I, Borràs E, Moles-Fernández A, Earl J, Cadiñanos J, Sánchez-Heras AB, Bigas A, Capellá G, Lázaro C. Moreno-Cabrera JM, et al. Among authors: bigas a. Database (Oxford). 2024 Jul 4;2024:baae055. doi: 10.1093/database/baae055. Database (Oxford). 2024. PMID: 38965703 Free PMC article.
Cis inhibition of NOTCH1 through JAGGED1 sustains embryonic hematopoietic stem cell fate.
Thambyrajah R, Maqueda M, Neo WH, Imbach K, Guillén Y, Grases D, Fadlullah Z, Gambera S, Matteini F, Wang X, Calero-Nieto FJ, Esteller M, Florian MC, Porta E, Benedito R, Göttgens B, Lacaud G, Espinosa L, Bigas A. Thambyrajah R, et al. Among authors: bigas a. Nat Commun. 2024 Feb 21;15(1):1604. doi: 10.1038/s41467-024-45716-y. Nat Commun. 2024. PMID: 38383534 Free PMC article.
126 results