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Mutation and repair induced by the carcinogen 2-(hydroxyamino)-1-methyl-6-phenylimidazo[4,5-b]pyridine (N-OH-PhIP) in the dihydrofolate reductase gene of Chinese hamster ovary cells and conformational modeling of the dG-C8-PhIP adduct in DNA.
Carothers AM, Yuan W, Hingerty BE, Broyde S, Grunberger D, Snyderwine EG. Carothers AM, et al. Among authors: hingerty be. Chem Res Toxicol. 1994 Mar-Apr;7(2):209-18. doi: 10.1021/tx00038a015. Chem Res Toxicol. 1994. PMID: 8199311
Solution conformation of [AF]dG opposite a -2 deletion site in a DNA duplex: intercalation of the covalently attached aminofluorene ring into the helix with base displacement of the C8-modified syn guanine and adjacent unpaired 3'-adenine into the major groove.
Mao B, Hingerty BE, Broyde S, Patel DJ. Mao B, et al. Among authors: hingerty be. Biochemistry. 1995 Dec 26;34(51):16641-53. doi: 10.1021/bi00051a012. Biochemistry. 1995. PMID: 8527437
The intercalative base displacement structure of the [AF]dG.2del 12-mer duplex exhibits several unusually shifted proton resonances that can be readily accounted for by the ring current contributions of the deoxyguanosine purine and carcinogen fluorene aromatic rings of th …
The intercalative base displacement structure of the [AF]dG.2del 12-mer duplex exhibits several unusually shifted proton resonances that can …
87 results