Borthwick NJ - Search Results

1

Presence of CD3+CD8+Bcl-2(low) lymphocytes undergoing apoptosis and activated macrophages in lymph nodes of HIV-1+ patients.

Bofill M, Gombert W, Borthwick NJ, Akbar AN, McLaughlin JE, Lee CA, Johnson MA, Pinching AJ, Janossy G. Bofill M, et al. Among authors: borthwick nj. Am J Pathol. 1995 Jun;146(6):1542-55. Am J Pathol. 1995. PMID: 7778692 Free PMC article.

2

The specific recognition by macrophages of CD8+,CD45RO+ T cells undergoing apoptosis: a mechanism for T cell clearance during resolution of viral infections.

Akbar AN, Savill J, Gombert W, Bofill M, Borthwick NJ, Whitelaw F, Grundy J, Janossy G, Salmon M. Akbar AN, et al. Among authors: borthwick nj. J Exp Med. 1994 Nov 1;180(5):1943-7. doi: 10.1084/jem.180.5.1943. J Exp Med. 1994. PMID: 7964470 Free PMC article.

3

Lymphocyte activation in HIV-1 infection. II. Functional defects of CD28- T cells.

Borthwick NJ, Bofill M, Gombert WM, Akbar AN, Medina E, Sagawa K, Lipman MC, Johnson MA, Janossy G. Borthwick NJ, et al. AIDS. 1994 Apr;8(4):431-41. doi: 10.1097/00002030-199404000-00004. AIDS. 1994. PMID: 8011246

4

Increased numbers of primed activated CD8+CD38+CD45RO+ T cells predict the decline of CD4+ T cells in HIV-1-infected patients.

Bofill M, Mocroft A, Lipman M, Medina E, Borthwick NJ, Sabin CA, Timms A, Winter M, Baptista L, Johnson MA, Lee CA, Phillips AN, Janossy G. Bofill M, et al. Among authors: borthwick nj. AIDS. 1996 Jul;10(8):827-34. doi: 10.1097/00002030-199607000-00005. AIDS. 1996. PMID: 8828739

5

Factors that influence activated CD8+ T-cell apoptosis in patients with acute herpesvirus infections: loss of costimulatory molecules CD28, CD5 and CD6 but relative maintenance of Bax and Bcl-X expression.

Borthwick NJ, Bofill M, Hassan I, Panayiotidis P, Janossy G, Salmon M, Akbar AN. Borthwick NJ, et al. Immunology. 1996 Aug;88(4):508-15. Immunology. 1996. PMID: 8881750 Free PMC article.

6

Fibroblasts prevent apoptosis of IL-2-deprived T cells without inducing proliferation: a selective effect on Bcl-XL expression.

Gombert W, Borthwick NJ, Wallace DL, Hyde H, Bofill M, Pilling D, Beverley PC, Janossy G, Salmon M, Akbar AN. Gombert W, et al. Among authors: borthwick nj. Immunology. 1996 Nov;89(3):397-404. doi: 10.1046/j.1365-2567.1996.d01-759.x. Immunology. 1996. PMID: 8958053 Free PMC article.

7

Upregulation of intracellular glutathione by fibroblast-derived factor(s): enhanced survival of activated T cells in the presence of low Bcl-2.

Hyde H, Borthwick NJ, Janossy G, Salmon M, Akbar AN. Hyde H, et al. Among authors: borthwick nj. Blood. 1997 Apr 1;89(7):2453-60. Blood. 1997. PMID: 9116289 Free article.

8

IL-7-dependent extrathymic expansion of CD45RA+ T cells enables preservation of a naive repertoire.

Soares MV, Borthwick NJ, Maini MK, Janossy G, Salmon M, Akbar AN. Soares MV, et al. Among authors: borthwick nj. J Immunol. 1998 Dec 1;161(11):5909-17. J Immunol. 1998. PMID: 9834071

9

Loss of CD28 expression on CD8(+) T cells is induced by IL-2 receptor gamma chain signalling cytokines and type I IFN, and increases susceptibility to activation-induced apoptosis.

Borthwick NJ, Lowdell M, Salmon M, Akbar AN. Borthwick NJ, et al. Int Immunol. 2000 Jul;12(7):1005-13. doi: 10.1093/intimm/12.7.1005. Int Immunol. 2000. PMID: 10882412

10

The significance of low bcl-2 expression by CD45RO T cells in normal individuals and patients with acute viral infections. The role of apoptosis in T cell memory.

Akbar AN, Borthwick N, Salmon M, Gombert W, Bofill M, Shamsadeen N, Pilling D, Pett S, Grundy JE, Janossy G. Akbar AN, et al. J Exp Med. 1993 Aug 1;178(2):427-38. doi: 10.1084/jem.178.2.427. J Exp Med. 1993. PMID: 8340752 Free PMC article.

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