Pastan I - Search Results

1

Efficient expression of functional human MDR1 gene in murine bone marrow after retroviral transduction of purified hematopoietic stem cells.

Licht T, Aksentijevich I, Gottesman MM, Pastan I. Licht T, et al. Among authors: pastan i. Blood. 1995 Jul 1;86(1):111-21. Blood. 1995. PMID: 7795216 Free article.

2

Expression of a human complementary DNA for the multidrug resistance gene in murine hematopoietic precursor cells with the use of retroviral gene transfer.

McLachlin JR, Eglitis MA, Ueda K, Kantoff PW, Pastan IH, Anderson WF, Gottesman MM. McLachlin JR, et al. Among authors: pastan ih. J Natl Cancer Inst. 1990 Aug 1;82(15):1260-3. doi: 10.1093/jnci/82.15.1260. J Natl Cancer Inst. 1990. PMID: 2374175

3

Selection of drug-resistant bone marrow cells in vivo after retroviral transfer of human MDR1.

Sorrentino BP, Brandt SJ, Bodine D, Gottesman M, Pastan I, Cline A, Nienhuis AW. Sorrentino BP, et al. Among authors: pastan i. Science. 1992 Jul 3;257(5066):99-103. doi: 10.1126/science.1352414. Science. 1992. PMID: 1352414

4

Identification of residues in the first cytoplasmic loop of P-glycoprotein involved in the function of chimeric human MDR1-MDR2 transporters.

Currier SJ, Kane SE, Willingham MC, Cardarelli CO, Pastan I, Gottesman MM. Currier SJ, et al. Among authors: pastan i. J Biol Chem. 1992 Dec 15;267(35):25153-9. J Biol Chem. 1992. PMID: 1360983 Free article.

5

Transgenic mice that express the human multidrug-resistance gene in bone marrow enable a rapid identification of agents that reverse drug resistance.

Mickisch GH, Merlino GT, Galski H, Gottesman MM, Pastan I. Mickisch GH, et al. Among authors: pastan i. Proc Natl Acad Sci U S A. 1991 Jan 15;88(2):547-51. doi: 10.1073/pnas.88.2.547. Proc Natl Acad Sci U S A. 1991. PMID: 1671173 Free PMC article.

6

Magnetic-affinity cell sorting of human multidrug-resistant cells.

Padmanabhan R, Tsuruo T, Kane SE, Willingham MC, Howard BH, Gottesman MM, Pastan I. Padmanabhan R, et al. Among authors: pastan i. J Natl Cancer Inst. 1991 Apr 17;83(8):565-9. doi: 10.1093/jnci/83.8.565. J Natl Cancer Inst. 1991. PMID: 1672384

7

New potent verapamil derivatives that reverse multidrug resistance in human renal carcinoma cells and in transgenic mice expressing the human MDR1 gene.

Mickisch GH, Merlino GT, Aiken PM, Gottesman MM, Pastan I. Mickisch GH, et al. Among authors: pastan i. J Urol. 1991 Aug;146(2):447-53. doi: 10.1016/s0022-5347(17)37822-9. J Urol. 1991. PMID: 1677434

8

Chemotherapy and chemosensitization of transgenic mice which express the human multidrug resistance gene in bone marrow: efficacy, potency, and toxicity.

Mickisch GH, Licht T, Merlino GT, Gottesman MM, Pastan I. Mickisch GH, et al. Among authors: pastan i. Cancer Res. 1991 Oct 1;51(19):5417-24. Cancer Res. 1991. PMID: 1680550

9

Multidrug resistant transgenic mice as a novel pharmacologic tool.

Mickisch GH, Pastan I, Gottesman MM. Mickisch GH, et al. Among authors: pastan i. Bioessays. 1991 Aug;13(8):381-7. doi: 10.1002/bies.950130804. Bioessays. 1991. PMID: 1683231 Review.

10

Transplantation of bone marrow cells from transgenic mice expressing the human MDR1 gene results in long-term protection against the myelosuppressive effect of chemotherapy in mice.

Mickisch GH, Aksentijevich I, Schoenlein PV, Goldstein LJ, Galski H, Stahle C, Sachs DH, Pastan I, Gottesman MM. Mickisch GH, et al. Among authors: pastan i. Blood. 1992 Feb 15;79(4):1087-93. Blood. 1992. PMID: 1737094 Free article.

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