Bowtell D - Search Results

1

A dominant-negative mutant of mSOS1 inhibits insulin-induced Ras activation and reveals Ras-dependent and -independent insulin signaling pathways.

Sakaue M, Bowtell D, Kasuga M. Sakaue M, et al. Among authors: bowtell d. Mol Cell Biol. 1995 Jan;15(1):379-88. doi: 10.1128/MCB.15.1.379. Mol Cell Biol. 1995. PMID: 7799946 Free PMC article.

2

The solution structure of the pleckstrin homology domain of mouse Son-of-sevenless 1 (mSos1).

Koshiba S, Kigawa T, Kim JH, Shirouzu M, Bowtell D, Yokoyama S. Koshiba S, et al. Among authors: bowtell d. J Mol Biol. 1997 Jun 20;269(4):579-91. doi: 10.1006/jmbi.1997.1041. J Mol Biol. 1997. PMID: 9217262

3

Activation of Ras and its downstream extracellular signal-regulated protein kinases by the CDC25 homology domain of mouse Son-of-sevenless 1 (mSos1).

Kim JH, Shirouzu M, Kataoka T, Bowtell D, Yokoyama S. Kim JH, et al. Among authors: bowtell d. Oncogene. 1998 May;16(20):2597-607. doi: 10.1038/sj.onc.1201822. Oncogene. 1998. PMID: 9632136

4

Shc, Grb2, Sos1, and a 150-kilodalton tyrosine-phosphorylated protein form complexes with Fms in hematopoietic cells.

Lioubin MN, Myles GM, Carlberg K, Bowtell D, Rohrschneider LR. Lioubin MN, et al. Among authors: bowtell d. Mol Cell Biol. 1994 Sep;14(9):5682-91. doi: 10.1128/mcb.14.9.5682-5691.1994. Mol Cell Biol. 1994. PMID: 7520523 Free PMC article.

5

Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient mice.

Murphy MA, Schnall RG, Venter DJ, Barnett L, Bertoncello I, Thien CB, Langdon WY, Bowtell DD. Murphy MA, et al. Among authors: bowtell dd. Mol Cell Biol. 1998 Aug;18(8):4872-82. doi: 10.1128/MCB.18.8.4872. Mol Cell Biol. 1998. PMID: 9671496 Free PMC article.

6

The Cbl proto-oncogene product negatively regulates the Src-family tyrosine kinase Fyn by enhancing its degradation.

Andoniou CE, Lill NL, Thien CB, Lupher ML Jr, Ota S, Bowtell DD, Scaife RM, Langdon WY, Band H. Andoniou CE, et al. Among authors: bowtell dd. Mol Cell Biol. 2000 Feb;20(3):851-67. doi: 10.1128/MCB.20.3.851-867.2000. Mol Cell Biol. 2000. PMID: 10629042 Free PMC article.

7

Generation and analysis of Siah2 mutant mice.

Frew IJ, Hammond VE, Dickins RA, Quinn JM, Walkley CR, Sims NA, Schnall R, Della NG, Holloway AJ, Digby MR, Janes PW, Tarlinton DM, Purton LE, Gillespie MT, Bowtell DD. Frew IJ, et al. Among authors: bowtell dd. Mol Cell Biol. 2003 Dec;23(24):9150-61. doi: 10.1128/MCB.23.24.9150-9161.2003. Mol Cell Biol. 2003. PMID: 14645526 Free PMC article.

8

B cell antigen receptor cross-linking induces phosphorylation of the p21ras oncoprotein activators SHC and mSOS1 as well as assembly of complexes containing SHC, GRB-2, mSOS1, and a 145-kDa tyrosine-phosphorylated protein.

Saxton TM, van Oostveen I, Bowtell D, Aebersold R, Gold MR. Saxton TM, et al. Among authors: bowtell d. J Immunol. 1994 Jul 15;153(2):623-36. J Immunol. 1994. PMID: 8021500

9

Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase.

Simon MA, Bowtell DD, Dodson GS, Laverty TR, Rubin GM. Simon MA, et al. Among authors: bowtell dd. Cell. 1991 Nov 15;67(4):701-16. doi: 10.1016/0092-8674(91)90065-7. Cell. 1991. PMID: 1934068

10

Normal p53 function in primary cells deficient for Siah genes.

Frew IJ, Dickins RA, Cuddihy AR, Del Rosario M, Reinhard C, O'Connell MJ, Bowtell DD. Frew IJ, et al. Among authors: bowtell dd. Mol Cell Biol. 2002 Dec;22(23):8155-64. doi: 10.1128/MCB.22.23.8155-8164.2002. Mol Cell Biol. 2002. PMID: 12417719 Free PMC article.

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