Fairbairn LJ - Search Results

1

O6-benzylguanine increases the sensitivity of human primary bone marrow cells to the cytotoxic effects of temozolomide.

Fairbairn LJ, Watson AJ, Rafferty JA, Elder RH, Margison GP. Fairbairn LJ, et al. Exp Hematol. 1995 Feb;23(2):112-6. Exp Hematol. 1995. PMID: 7828668

2

Long-term protection of hematopoiesis against the cytotoxic effects of multiple doses of nitrosourea by retrovirus-mediated expression of human O6-alkylguanine-DNA-alkyltransferase.

Jelínek J, Fairbairn LJ, Dexter TM, Rafferty JA, Stocking C, Ostertag W, Margison GP. Jelínek J, et al. Among authors: fairbairn lj. Blood. 1996 Mar 1;87(5):1957-61. Blood. 1996. PMID: 8634444 Free article.

3

Protection of mammalian cells against chloroethylating agent toxicity by an O6-benzylguanine-resistant mutant of human O6-alkylguanine-DNA alkyltransferase.

Hickson I, Fairbairn LJ, Chinnasamy N, Dexter TM, Margison GP, Rafferty JA. Hickson I, et al. Among authors: fairbairn lj. Gene Ther. 1996 Oct;3(10):868-77. Gene Ther. 1996. PMID: 8908500

4

Chemoprotection of normal tissues by transfer of drug resistance genes.

Rafferty JA, Hickson I, Chinnasamy N, Lashford LS, Margison GP, Dexter TM, Fairbairn LJ. Rafferty JA, et al. Among authors: fairbairn lj. Cancer Metastasis Rev. 1996 Sep;15(3):365-83. doi: 10.1007/BF00046348. Cancer Metastasis Rev. 1996. PMID: 9034597 Review.

5

O6-benzylguanine potentiates the in vivo toxicity and clastogenicity of temozolomide and BCNU in mouse bone marrow.

Chinnasamy N, Rafferty JA, Hickson I, Ashby J, Tinwell H, Margison GP, Dexter TM, Fairbairn LJ. Chinnasamy N, et al. Among authors: fairbairn lj. Blood. 1997 Mar 1;89(5):1566-73. Blood. 1997. PMID: 9057638 Free article.

6

Modulation of O6-alkylating agent induced clastogenicity by enhanced DNA repair capacity of bone marrow cells.

Chinnasamy N, Fairbairn LJ, Laher J, Willington MA, Rafferty JA. Chinnasamy N, et al. Among authors: fairbairn lj. Mutat Res. 1998 Aug 7;416(1-2):1-10. doi: 10.1016/s1383-5718(98)00087-4. Mutat Res. 1998. PMID: 9725988

7

Chemoprotective gene transfer I: transduction of human haemopoietic progenitors with O6-benzylguanine-resistant O6-alkylguanine-DNA alkyltransferase attenuates the toxic effects of O6-alkylating agents in vitro.

Hickson I, Fairbairn LJ, Chinnasamy N, Lashford LS, Thatcher N, Margison GP, Dexter TM, Rafferty JA. Hickson I, et al. Among authors: fairbairn lj. Gene Ther. 1998 Jun;5(6):835-41. doi: 10.1038/sj.gt.3300698. Gene Ther. 1998. PMID: 9747464

8

Chemoprotective gene transfer II: multilineage in vivo protection of haemopoiesis against the effects of an antitumour agent by expression of a mutant human O6-alkylguanine-DNA alkyltransferase.

Chinnasamy N, Rafferty JA, Hickson I, Lashford LS, Longhurst SJ, Thatcher N, Margison GP, Dexter TM, Fairbairn LJ. Chinnasamy N, et al. Among authors: fairbairn lj. Gene Ther. 1998 Jun;5(6):842-7. doi: 10.1038/sj.gt.3300699. Gene Ther. 1998. PMID: 9747465

9

Engineering drug resistance in human cells.

Fairbairn LJ, Rafferty JA, Lashford LS. Fairbairn LJ, et al. Bone Marrow Transplant. 2000 May;25 Suppl 2:S110-3. doi: 10.1038/sj.bmt.1702366. Bone Marrow Transplant. 2000. PMID: 10933202

10

Enhanced in vivo selection of bone marrow cells by retroviral-mediated coexpression of mutant O6-methylguanine-DNA-methyltransferase and HOXB4.

Milsom MD, Woolford LB, Margison GP, Humphries RK, Fairbairn LJ. Milsom MD, et al. Among authors: fairbairn lj. Mol Ther. 2004 Nov;10(5):862-73. doi: 10.1016/j.ymthe.2004.07.019. Mol Ther. 2004. PMID: 15509504 Free article.

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