Skibo EB - Search Results

1

Pyrrolo[1,2-a]benzimidazole-based quinones and iminoquinones. The role of the 3-substituent on cytotoxicity.

Schulz WG, Islam I, Skibo EB. Schulz WG, et al. Among authors: skibo eb. J Med Chem. 1995 Jan 6;38(1):109-18. doi: 10.1021/jm00001a016. J Med Chem. 1995. PMID: 7837221

2

Pyrrolo[1,2-a]benzimidazole-based aziridinyl quinones. A new class of DNA cleaving agent exhibiting G and A base specificity.

Skibo EB, Schulz WG. Skibo EB, et al. J Med Chem. 1993 Oct 15;36(21):3050-5. doi: 10.1021/jm00073a002. J Med Chem. 1993. PMID: 8230090

3

Structure-activity studies of benzimidazole-based DNA-cleaving agents. Comparison of benzimidazole, pyrrolobenzimidazole, and tetrahydropyridobenzimidazole analogues.

Skibo EB, Islam I, Heileman MJ, Schulz WG. Skibo EB, et al. J Med Chem. 1994 Jan 7;37(1):78-92. doi: 10.1021/jm00027a010. J Med Chem. 1994. PMID: 8289204

4

Evidence for DNA phosphate backbone alkylation and cleavage by pyrrolo[1,2-a]benzimidazoles: small molecules capable of causing base-pair-specific phosphodiester bond hydrolysis.

Schulz WG, Nieman RA, Skibo EB. Schulz WG, et al. Among authors: skibo eb. Proc Natl Acad Sci U S A. 1995 Dec 5;92(25):11854-8. doi: 10.1073/pnas.92.25.11854. Proc Natl Acad Sci U S A. 1995. PMID: 8524862 Free PMC article.

5

Inhibitors of topoisomerase II based on the benzodiimidazole and dipyrroloimidazobenzimidazole ring systems: controlling DT-diaphorase reductive inactivation with steric bulk.

Schulz WG, Skibo EB. Schulz WG, et al. Among authors: skibo eb. J Med Chem. 2000 Feb 24;43(4):629-38. doi: 10.1021/jm990210q. J Med Chem. 2000. PMID: 10691689

6

Structure-activity studies of antitumor agents based on pyrrolo[1,2-a]benzimidazoles: new reductive alkylating DNA cleaving agents.

Islam I, Skibo EB, Dorr RT, Alberts DS. Islam I, et al. Among authors: skibo eb. J Med Chem. 1991 Oct;34(10):2954-61. doi: 10.1021/jm00114a003. J Med Chem. 1991. PMID: 1920349

7

Design of highly active analogues of the pyrrolo[1,2-a]benzimidazole antitumor agents.

Craigo WA, LeSueur BW, Skibo EB. Craigo WA, et al. Among authors: skibo eb. J Med Chem. 1999 Aug 26;42(17):3324-33. doi: 10.1021/jm990029h. J Med Chem. 1999. PMID: 10464019

8

A comparison of the cytotoxic and physical properties of aziridinyl quinone derivatives based on the pyrrolo[1,2-a]benzimidazole and pyrrolo[1,2-a]indole ring systems.

Boruah RC, Skibo EB. Boruah RC, et al. Among authors: skibo eb. J Med Chem. 1994 May 27;37(11):1625-31. doi: 10.1021/jm00037a013. J Med Chem. 1994. PMID: 8201596

9

Chemistry of the pyrrolo[1,2-alpha]benzimidazole antitumor agents: influence of the 7-substituent on the ability to alkylate DNA and inhibit topoisomerase II.

Zhou R, Skibo EB. Zhou R, et al. Among authors: skibo eb. J Med Chem. 1996 Oct 11;39(21):4321-31. doi: 10.1021/jm960064d. J Med Chem. 1996. PMID: 8863809

10

Studies of pyrrolo[1,2-alpha]benzimidazolequinone DT-diaphorase substrate activity, topoisomerase II inhibition activity, and DNA reductive alkylation.

Skibo EB, Gordon S, Bess L, Boruah R, Heileman MJ. Skibo EB, et al. J Med Chem. 1997 Apr 25;40(9):1327-39. doi: 10.1021/jm960546p. J Med Chem. 1997. PMID: 9135030

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

39 results

Search Page

Filters