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Loss of insulin signaling in vascular endothelial cells accelerates atherosclerosis in apolipoprotein E null mice.
Rask-Madsen C, Li Q, Freund B, Feather D, Abramov R, Wu IH, Chen K, Yamamoto-Hiraoka J, Goldenbogen J, Sotiropoulos KB, Clermont A, Geraldes P, Dall'Osso C, Wagers AJ, Huang PL, Rekhter M, Scalia R, Kahn CR, King GL. Rask-Madsen C, et al. Among authors: wu ih. Cell Metab. 2010 May 5;11(5):379-89. doi: 10.1016/j.cmet.2010.03.013. Cell Metab. 2010. PMID: 20444418 Free PMC article.
Insulin decreases atherosclerosis by inducing endothelin receptor B expression.
Park K, Mima A, Li Q, Rask-Madsen C, He P, Mizutani K, Katagiri S, Maeda Y, Wu IH, Khamaisi M, Preil SR, Maddaloni E, Sørensen D, Rasmussen LM, Huang PL, King GL. Park K, et al. Among authors: wu ih. JCI Insight. 2016 May 5;1(6):e86574. doi: 10.1172/jci.insight.86574. JCI Insight. 2016. PMID: 27200419 Free PMC article.
Pyruvate kinase M2 activation may protect against the progression of diabetic glomerular pathology and mitochondrial dysfunction.
Qi W, Keenan HA, Li Q, Ishikado A, Kannt A, Sadowski T, Yorek MA, Wu IH, Lockhart S, Coppey LJ, Pfenninger A, Liew CW, Qiang G, Burkart AM, Hastings S, Pober D, Cahill C, Niewczas MA, Israelsen WJ, Tinsley L, Stillman IE, Amenta PS, Feener EP, Vander Heiden MG, Stanton RC, King GL. Qi W, et al. Among authors: wu ih. Nat Med. 2017 Jun;23(6):753-762. doi: 10.1038/nm.4328. Epub 2017 Apr 24. Nat Med. 2017. PMID: 28436957 Free PMC article.
212 results