Yamazaki H - Search Results

1

Fluorescence in situ hybridization analysis of chromosomal localization of three human cytochrome P450 2C genes (CYP2C8, 2C9, and 2C10) at 10q24.1.

Inoue K, Inazawa J, Suzuki Y, Shimada T, Yamazaki H, Guengerich FP, Abe T. Inoue K, et al. Among authors: yamazaki h. Jpn J Hum Genet. 1994 Sep;39(3):337-43. doi: 10.1007/BF01874052. Jpn J Hum Genet. 1994. PMID: 7841444

2

Oxidation of xenobiotics by recombinant human cytochrome P450 1B1.

Shimada T, Gillam EM, Sutter TR, Strickland PT, Guengerich FP, Yamazaki H. Shimada T, et al. Among authors: yamazaki h. Drug Metab Dispos. 1997 May;25(5):617-22. Drug Metab Dispos. 1997. PMID: 9152602

3

Relationship between CYP2C9 and 2C19 genotypes and tolbutamide methyl hydroxylation and S-mephenytoin 4'-hydroxylation activities in livers of Japanese and Caucasian populations.

Inoue K, Yamazaki H, Imiya K, Akasaka S, Guengerich FP, Shimada T. Inoue K, et al. Among authors: yamazaki h. Pharmacogenetics. 1997 Apr;7(2):103-13. doi: 10.1097/00008571-199704000-00003. Pharmacogenetics. 1997. PMID: 9170147

4

Reconstitution of recombinant cytochrome P450 2C10(2C9) and comparison with cytochrome P450 3A4 and other forms: effects of cytochrome P450-P450 and cytochrome P450-b5 interactions.

Yamazaki H, Gillam EM, Dong MS, Johnson WW, Guengerich FP, Shimada T. Yamazaki H, et al. Arch Biochem Biophys. 1997 Jun 15;342(2):329-37. doi: 10.1006/abbi.1997.0125. Arch Biochem Biophys. 1997. PMID: 9186495

CYP2C10 required cytochrome b5 (b5) for optimal rates of tolbutamide and S-warfarin oxidations and b5 could be replaced by apo-b5; apo-b5 and b5 effects on the reconstituted systems have already been reported in systems containing CYP3A4 for the oxidation of testosterone and nife …

CYP2C10 required cytochrome b5 (b5) for optimal rates of tolbutamide and S-warfarin oxidations and b5 could be replaced by apo-b5; apo-b5 an …

5

Progesterone and testosterone hydroxylation by cytochromes P450 2C19, 2C9, and 3A4 in human liver microsomes.

Yamazaki H, Shimada T. Yamazaki H, et al. Arch Biochem Biophys. 1997 Oct 1;346(1):161-9. doi: 10.1006/abbi.1997.0302. Arch Biochem Biophys. 1997. PMID: 9328296

6

Roles of two allelic variants (Arg144Cys and Ile359Leu) of cytochrome P4502C9 in the oxidation of tolbutamide and warfarin by human liver microsomes.

Yamazaki H, Inoue K, Shimada T. Yamazaki H, et al. Xenobiotica. 1998 Feb;28(2):103-15. doi: 10.1080/004982598239614. Xenobiotica. 1998. PMID: 9522436

7

Linkage between the distribution of mutations in the CYP2C18 and CYP2C19 genes in the Japanese and Caucasian.

Inoue K, Yamazaki H, Shimada T. Inoue K, et al. Among authors: yamazaki h. Xenobiotica. 1998 Apr;28(4):403-11. doi: 10.1080/004982598239506. Xenobiotica. 1998. PMID: 9604303

8

Roles of cytochromes P450 1A2 and 3A4 in the oxidation of estradiol and estrone in human liver microsomes.

Yamazaki H, Shaw PM, Guengerich FP, Shimada T. Yamazaki H, et al. Chem Res Toxicol. 1998 Jun;11(6):659-65. doi: 10.1021/tx970217f. Chem Res Toxicol. 1998. PMID: 9625734

9

Comparative studies on the catalytic roles of cytochrome P450 2C9 and its Cys- and Leu-variants in the oxidation of warfarin, flurbiprofen, and diclofenac by human liver microsomes.

Yamazaki H, Inoue K, Chiba K, Ozawa N, Kawai T, Suzuki Y, Goldstein JA, Guengerich FP, Shimada T. Yamazaki H, et al. Biochem Pharmacol. 1998 Jul 15;56(2):243-51. doi: 10.1016/s0006-2952(98)00133-6. Biochem Pharmacol. 1998. PMID: 9698079

10

Comparative studies of in vitro inhibition of cytochrome P450 3A4-dependent testosterone 6beta-hydroxylation by roxithromycin and its metabolites, troleandomycin, and erythromycin.

Yamazaki H, Shimada T. Yamazaki H, et al. Drug Metab Dispos. 1998 Nov;26(11):1053-7. Drug Metab Dispos. 1998. PMID: 9806945

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