Denner K - Search Results

1

Amino acid substitution R384P in aldosterone synthase causes corticosterone methyloxidase type I deficiency.

Geley S, Jöhrer K, Peter M, Denner K, Bernhardt R, Sippell WG, Kofler R. Geley S, et al. Among authors: denner k. J Clin Endocrinol Metab. 1995 Feb;80(2):424-9. doi: 10.1210/jcem.80.2.7852500. J Clin Endocrinol Metab. 1995. PMID: 7852500

2

Cloning of CYP11B1 and CYP11B2 from normal human adrenal and their functional expression in COS-7 and V79 Chinese hamster cells.

Denner K, Doehmer J, Bernhardt R. Denner K, et al. Endocr Res. 1995 Feb-May;21(1-2):443-8. doi: 10.3109/07435809509030460. Endocr Res. 1995. PMID: 7588408

3

Differential regulation of 11 beta-hydroxylase and aldosterone synthase in human adrenocortical H295R cells.

Denner K, Rainey WE, Pezzi V, Bird IM, Bernhardt R, Mathis JM. Denner K, et al. Mol Cell Endocrinol. 1996 Jul 23;121(1):87-91. doi: 10.1016/0303-7207(96)03853-1. Mol Cell Endocrinol. 1996. PMID: 8865169

4

Conferring aldosterone synthesis to human CYP11B1 by replacing key amino acid residues with CYP11B2-specific ones.

Böttner B, Denner K, Bernhardt R. Böttner B, et al. Among authors: denner k. Eur J Biochem. 1998 Mar 15;252(3):458-66. doi: 10.1046/j.1432-1327.1998.2520458.x. Eur J Biochem. 1998. PMID: 9546661 Free article.

5

Human adrenal CYP11B1: localization by in situ-hybridization and functional expression in cell cultures.

Erdmann B, Denner K, Gerst H, Lenz D, Bernhardt R. Erdmann B, et al. Among authors: denner k. Endocr Res. 1995 Feb-May;21(1-2):425-35. doi: 10.3109/07435809509030458. Endocr Res. 1995. PMID: 7588406

6

Cloning and stable expression of the human mitochondrial cytochrome P45011B1 cDNA in V79 Chinese hamster cells and their application for testing of potential inhibitors.

Denner K, Vogel R, Schmalix W, Doehmer J, Bernhardt R. Denner K, et al. Pharmacogenetics. 1995 Apr;5(2):89-96. doi: 10.1097/00008571-199504000-00005. Pharmacogenetics. 1995. PMID: 7663533

7

Functional characterization of atherosclerosis-associated Ser128Arg and Leu554Phe E-selectin mutations.

Wenzel K, Stahn R, Speer A, Denner K, Gläser C, Affeldt M, Moobed M, Scheer A, Baumann G, Felix SB. Wenzel K, et al. Among authors: denner k. Biol Chem. 1999 Jun;380(6):661-7. doi: 10.1515/BC.1999.082. Biol Chem. 1999. PMID: 10430030

8

Carrier-mediated residual K+ and Na+ transport of human red blood cells.

Denner K, Heinrich R, Bernhardt I. Denner K, et al. J Membr Biol. 1993 Mar;132(2):137-45. doi: 10.1007/BF00239003. J Membr Biol. 1993. PMID: 8496945

9

Damage Incorporated: Discovery of the Potent, Highly Selective, Orally Available ATR Inhibitor BAY 1895344 with Favorable Pharmacokinetic Properties and Promising Efficacy in Monotherapy and in Combination Treatments in Preclinical Tumor Models.

Lücking U, Wortmann L, Wengner AM, Lefranc J, Lienau P, Briem H, Siemeister G, Bömer U, Denner K, Schäfer M, Koppitz M, Eis K, Bartels F, Bader B, Bone W, Moosmayer D, Holton SJ, Eberspächer U, Grudzinska-Goebel J, Schatz C, Deeg G, Mumberg D, von Nussbaum F. Lücking U, et al. Among authors: denner k. J Med Chem. 2020 Jul 9;63(13):7293-7325. doi: 10.1021/acs.jmedchem.0c00369. Epub 2020 Jun 28. J Med Chem. 2020. PMID: 32502336

10

Changing for the Better: Discovery of the Highly Potent and Selective CDK9 Inhibitor VIP152 Suitable for Once Weekly Intravenous Dosing for the Treatment of Cancer.

Lücking U, Kosemund D, Böhnke N, Lienau P, Siemeister G, Denner K, Bohlmann R, Briem H, Terebesi I, Bömer U, Schäfer M, Ince S, Mumberg D, Scholz A, Izumi R, Hwang S, von Nussbaum F. Lücking U, et al. Among authors: denner k. J Med Chem. 2021 Aug 12;64(15):11651-11674. doi: 10.1021/acs.jmedchem.1c01000. Epub 2021 Jul 15. J Med Chem. 2021. PMID: 34264057

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