Nichols CL - Search Results

1

Chemoimmunoconjugate development for ovarian carcinoma therapy: preclinical studies with vinca alkaloid-monoclonal antibody constructs.

Apelgren LD, Bailey DL, Briggs SL, Barton RL, Guttman-Carlisle D, Koppel GA, Nichols CL, Scott WL, Lindstrom TD, Baker AL, et al. Apelgren LD, et al. Among authors: nichols cl. Bioconjug Chem. 1993 Mar-Apr;4(2):121-6. doi: 10.1021/bc00020a003. Bioconjug Chem. 1993. PMID: 7873643

2

In vivo antitumor activity of a panel of four monoclonal antibody-vinca alkaloid immunoconjugates which bind to three distinct epitopes of carcinoembryonic antigen.

Starling JJ, Maciak RS, Hinson NA, Nichols CL, Briggs SL, Laguzza BC, Smith W, Corvalan JR. Starling JJ, et al. Among authors: nichols cl. Bioconjug Chem. 1992 Jul-Aug;3(4):315-22. doi: 10.1021/bc00016a010. Bioconjug Chem. 1992. PMID: 1382618

3

New antitumor monoclonal antibody-vinca conjugates LY203725 and related compounds: design, preparation, and representative in vivo activity.

Laguzza BC, Nichols CL, Briggs SL, Cullinan GJ, Johnson DA, Starling JJ, Baker AL, Bumol TF, Corvalan JR. Laguzza BC, et al. Among authors: nichols cl. J Med Chem. 1989 Mar;32(3):548-55. doi: 10.1021/jm00123a007. J Med Chem. 1989. PMID: 2783975

4

In vivo efficacy of monoclonal antibody-drug conjugates of three different subisotypes which bind the human tumor-associated antigen defined by the KS1/4 monoclonal antibody.

Starling JJ, Maciak RS, Hinson NA, Nichols CL, Briggs SL, Laguzza BC. Starling JJ, et al. Among authors: nichols cl. Cancer Immunol Immunother. 1989;28(3):171-8. doi: 10.1007/BF00204985. Cancer Immunol Immunother. 1989. PMID: 2784353 Free PMC article.

5

Protein conjugates of defined structure: synthesis and use of a new carrier molecule.

Vilaseca LA, Rose K, Werlen R, Meunier A, Offord RE, Nichols CL, Scott WL. Vilaseca LA, et al. Among authors: nichols cl. Bioconjug Chem. 1993 Nov-Dec;4(6):515-20. doi: 10.1021/bc00024a014. Bioconjug Chem. 1993. PMID: 8305521

6

Dexmedetomidine prolongs the duration of action of mepivacaine on anesthesia of the palmar digital nerves of horses.

Nichols CL, Doherty TJ, Schumacher J, Jones PD, Sun X. Nichols CL, et al. Am J Vet Res. 2021 Nov 30;83(2):114-118. doi: 10.2460/ajvr.20.10.0188. Am J Vet Res. 2021. PMID: 34851852 Free article.

7

Efficacy and duration of effect for liposomal bupivacaine when administered perineurally to the palmar digital nerves of horses.

McCracken MJ, Schumacher J, Doherty TJ, Sun X, Nichols CL, Olivarez J. McCracken MJ, et al. Among authors: nichols cl. Am J Vet Res. 2020 May;81(5):400-405. doi: 10.2460/ajvr.81.5.400. Am J Vet Res. 2020. PMID: 32343175 Free article.

8

Pyrimido[4,5-d]azepines as potent and selective 5-HT2C receptor agonists: design, synthesis, and evaluation of PF-3246799 as a treatment for urinary incontinence.

Andrews MD, Fish PV, Blagg J, Brabham TK, Brennan PE, Bridgeland A, Brown AD, Bungay PJ, Conlon KM, Edmunds NJ, af Forselles K, Gibbons CP, Green MP, Hanton G, Holbrook M, Jessiman AS, McIntosh K, McMurray G, Nichols CL, Root JA, Storer RI, Sutton MR, Ward RV, Westbrook D, Whitlock GA. Andrews MD, et al. Among authors: nichols cl. Bioorg Med Chem Lett. 2011 May 1;21(9):2715-20. doi: 10.1016/j.bmcl.2010.11.120. Epub 2010 Dec 4. Bioorg Med Chem Lett. 2011. PMID: 21195614

9

Design and synthesis of piperazinylpyrimidinones as novel selective 5-HT(2C) agonists.

Andrews MD, Green MP, Allerton CM, Batchelor DV, Blagg J, Brown AD, Gordon DW, McMurray G, Millns DJ, Nichols CL, Watson L. Andrews MD, et al. Among authors: nichols cl. Bioorg Med Chem Lett. 2009 Sep 15;19(18):5346-50. doi: 10.1016/j.bmcl.2009.07.133. Epub 2009 Aug 6. Bioorg Med Chem Lett. 2009. PMID: 19692241

10

Design and synthesis of a functionally selective D3 agonist and its in vivo delivery via the intranasal route.

Blagg J, Allerton CM, Batchelor DV, Baxter AD, Burring DJ, Carr CL, Cook AS, Nichols CL, Phipps J, Sanderson VG, Verrier H, Wong S. Blagg J, et al. Among authors: nichols cl. Bioorg Med Chem Lett. 2007 Dec 15;17(24):6691-6. doi: 10.1016/j.bmcl.2007.10.059. Epub 2007 Oct 22. Bioorg Med Chem Lett. 2007. PMID: 17976986

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