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Two cofactors and cytoplasmic chaperonin are required for the folding of alpha- and beta-tubulin.
Gao Y, Vainberg IE, Chow RL, Cowan NJ. Gao Y, et al. Mol Cell Biol. 1993 Apr;13(4):2478-85. doi: 10.1128/mcb.13.4.2478-2485.1993. Mol Cell Biol. 1993. PMID: 8096061 Free PMC article.
We recently identified a cytoplasmic chaperonin as an 800-kDa multisubunit toroid which forms a binary complex with unfolded actin; the correctly folded polypeptide is released upon incubation with Mg-ATP (Y. Gao, J. O. Thomas, R. L. Chow, G.-H. Lee, and N. J. Cowan …
We recently identified a cytoplasmic chaperonin as an 800-kDa multisubunit toroid which forms a binary complex with unfolded actin; the corr …
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