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Neoantigen DNA vaccines are safe, feasible, and induce neoantigen-specific immune responses in triple-negative breast cancer patients.
Zhang X, Goedegebuure SP, Chen MY, Mishra R, Zhang F, Yu YY, Singhal K, Li L, Gao F, Myers NB, Vickery T, Hundal J, McLellan MD, Sturmoski MA, Kim SW, Chen I, Davidson JT 4th, Sankpal NV, Myles S, Suresh R, Ma CX, Foluso A, Wang-Gillam A, Davies S, Hagemann IS, Mardis ER, Griffith O, Griffith M, Miller CA, Hansen TH, Fleming TP, Schreiber RD, Gillanders WE. Zhang X, et al. Among authors: schreiber rd. Genome Med. 2024 Nov 14;16(1):131. doi: 10.1186/s13073-024-01388-3. Genome Med. 2024. PMID: 39538331 Free PMC article. Clinical Trial.
Neoantigen-specific cytotoxic Tr1 CD4 T cells suppress cancer immunotherapy.
Sultan H, Takeuchi Y, Ward JP, Sharma N, Liu TT, Sukhov V, Firulyova M, Song Y, Ameh S, Brioschi S, Khantakova D, Arthur CD, White JM, Kohlmiller H, Salazar AM, Burns R, Costa HA, Moynihan KD, Yeung YA, Djuretic I, Schumacher TN, Sheehan KCF, Colonna M, Allison JP, Murphy KM, Artyomov MN, Schreiber RD. Sultan H, et al. Among authors: schreiber rd. Nature. 2024 Aug;632(8023):182-191. doi: 10.1038/s41586-024-07752-y. Epub 2024 Jul 24. Nature. 2024. PMID: 39048822 Free PMC article.
TREM2 deficiency reprograms intestinal macrophages and microbiota to enhance anti-PD-1 tumor immunotherapy.
Di Luccia B, Molgora M, Khantakova D, Jaeger N, Chang HW, Czepielewski RS, Helmink BA, Onufer EJ, Fachi JL, Bhattarai B, Trsan T, Rodrigues PF, Hou J, Bando JK, da Silva CS, Cella M, Gilfillan S, Schreiber RD, Gordon JI, Colonna M. Di Luccia B, et al. Among authors: schreiber rd. Sci Immunol. 2024 May 17;9(95):eadi5374. doi: 10.1126/sciimmunol.adi5374. Epub 2024 May 17. Sci Immunol. 2024. PMID: 38758808 Free PMC article.
Neoantigen landscape supports feasibility of personalized cancer vaccine for follicular lymphoma.
Ramirez CA, Becker-Hapak M, Singhal K, Russler-Germain DA, Frenkel F, Barnell EK, McClain ED, Desai S, Schappe T, Onyeador OC, Kudryashova O, Belousov V, Bagaev A, Ocheredko E, Kiwala S, Hundal J, Skidmore ZL, Watkins MP, Mooney TB, Walker JR, Krysiak K, Gomez F, Fronick CC, Fulton RS, Schreiber RD, Mehta-Shah N, Cashen AF, Kahl BS, Ataullakhanov R, Bartlett NL, Griffith M, Griffith OL, Fehniger TA. Ramirez CA, et al. Among authors: schreiber rd. Blood Adv. 2024 Aug 13;8(15):4035-4049. doi: 10.1182/bloodadvances.2022007792. Blood Adv. 2024. PMID: 38713894 Free PMC article. Clinical Trial.
316 results