Scopes DI - Search Results

1

Bromobenzofuran-based non-peptide antagonists of angiotensin II: GR138950, a potent antihypertensive agent with high oral bioavailability.

Judd DB, Dowle MD, Middlemiss D, Scopes DI, Ross BC, Jack TI, Pass M, Tranquillini E, Hobson JE, Panchal TA, et al. Judd DB, et al. Among authors: scopes di. J Med Chem. 1994 Sep 16;37(19):3108-20. doi: 10.1021/jm00045a016. J Med Chem. 1994. PMID: 7932534

2

Pharmacological profile of GR117289 in vitro: a novel, potent and specific non-peptide angiotensin AT1 receptor antagonist.

Robertson MJ, Barnes JC, Drew GM, Clark KL, Marshall FH, Michel A, Middlemiss D, Ross BC, Scopes D, Dowle MD. Robertson MJ, et al. Br J Pharmacol. 1992 Dec;107(4):1173-80. doi: 10.1111/j.1476-5381.1992.tb13425.x. Br J Pharmacol. 1992. PMID: 1467838 Free PMC article.

3

4-[(Alkylamino)methyl]furo[3,2-c]pyridines: a new series of selective kappa-receptor agonists.

Naylor A, Judd DB, Scopes DI, Hayes AG, Birch PJ. Naylor A, et al. Among authors: scopes di. J Med Chem. 1994 Jul 8;37(14):2138-44. doi: 10.1021/jm00040a004. J Med Chem. 1994. PMID: 8035420

4

A potent new class of kappa-receptor agonist: 4-substituted 1-(arylacetyl)-2-[(dialkylamino)methyl]piperazines.

Naylor A, Judd DB, Lloyd JE, Scopes DI, Hayes AG, Birch PJ. Naylor A, et al. Among authors: scopes di. J Med Chem. 1993 Jul 23;36(15):2075-83. doi: 10.1021/jm00067a004. J Med Chem. 1993. PMID: 8393489

5

Synthesis, antinociceptive activity, and opioid receptor profiles of substituted trans-3-(decahydro- and octahydro-4a-isoquinolinyl)phenols.

Judd DB, Brown DS, Lloyd JE, McElroy AB, Scopes DI, Birch PJ, Hayes AG, Sheehan MJ. Judd DB, et al. Among authors: scopes di. J Med Chem. 1992 Jan;35(1):48-56. doi: 10.1021/jm00079a005. J Med Chem. 1992. PMID: 1310115

6

New kappa-receptor agonists based upon a 2-[(alkylamino)methyl]piperidine nucleus.

Scopes DI, Hayes NF, Bays DE, Belton D, Brain J, Brown DS, Judd DB, McElroy AB, Meerholz CA, Naylor A, et al. Scopes DI, et al. J Med Chem. 1992 Feb 7;35(3):490-501. doi: 10.1021/jm00081a009. J Med Chem. 1992. PMID: 1310743

7

Neuroprotective actions of GR89696, a highly potent and selective kappa-opioid receptor agonist.

Birch PJ, Rogers H, Hayes AG, Hayward NJ, Tyers MB, Scopes DI, Naylor A, Judd DB. Birch PJ, et al. Among authors: scopes di. Br J Pharmacol. 1991 Jul;103(3):1819-23. doi: 10.1111/j.1476-5381.1991.tb09869.x. Br J Pharmacol. 1991. PMID: 1657267 Free PMC article.

8

A series of novel, highly potent and selective agonists for the kappa-opioid receptor.

Hayes AG, Birch PJ, Hayward NJ, Sheehan MJ, Rogers H, Tyers MB, Judd DB, Scopes DI, Naylor A. Hayes AG, et al. Among authors: scopes di. Br J Pharmacol. 1990 Dec;101(4):944-8. doi: 10.1111/j.1476-5381.1990.tb14185.x. Br J Pharmacol. 1990. PMID: 1964823 Free PMC article.

9

GR94839, a kappa-opioid agonist with limited access to the central nervous system, has antinociceptive activity.

Rogers H, Birch PJ, Harrison SM, Palmer E, Manchee GR, Judd DB, Naylor A, Scopes DI, Hayes AG. Rogers H, et al. Among authors: scopes di. Br J Pharmacol. 1992 Aug;106(4):783-9. doi: 10.1111/j.1476-5381.1992.tb14413.x. Br J Pharmacol. 1992. PMID: 1327387 Free PMC article.

10

Evolution of a novel series of [(N,N-dimethylamino)propyl]- and piperazinylbenzanilides as the first selective 5-HT1D antagonists.

Clitherow JW, Scopes DI, Skingle M, Jordan CC, Feniuk W, Campbell IB, Carter MC, Collington EW, Connor HE, Higgins GA, et al. Clitherow JW, et al. Among authors: scopes di. J Med Chem. 1994 Jul 22;37(15):2253-7. doi: 10.1021/jm00041a001. J Med Chem. 1994. PMID: 8057272 No abstract available.

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