Chang KC - Search Results

1

Cardiovascular effect of a naphthylmethyl substituted tetrahydroisoquinoline, YS 49, in rat and rabbit.

Lee YS, Kim CH, Yun-Choi HS, Chang KC. Lee YS, et al. Among authors: chang kc. Life Sci. 1994;55(21):PL415-20. doi: 10.1016/0024-3205(94)00335-1. Life Sci. 1994. PMID: 7968232

2

A synthetic isoquinoline alkaloid, 1-(beta-naphthylmethyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (YS 51), reduces inducible nitric oxide synthase expression and improves survival in a rodent model of endotoxic shock.

Kang YJ, Seo SJ, Yun-Choi HS, Lee DH, Kim YM, Chang KC. Kang YJ, et al. Among authors: chang kc. J Pharmacol Exp Ther. 2002 May;301(2):561-7. doi: 10.1124/jpet.301.2.561. J Pharmacol Exp Ther. 2002. PMID: 11961057

3

YS 49, 1-(alpha-naphtylmethyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, regulates angiotensin II-stimulated ROS production, JNK phosphorylation and vascular smooth muscle cell proliferation via the induction of heme oxygenase-1.

Sun JJ, Kim HJ, Seo HG, Lee JH, Yun-Choi HS, Chang KC. Sun JJ, et al. Among authors: chang kc. Life Sci. 2008 Mar 12;82(11-12):600-7. doi: 10.1016/j.lfs.2007.12.015. Epub 2007 Dec 26. Life Sci. 2008. PMID: 18262205

4

Prevention of the expression of inducible nitric oxide synthase by a novel positive inotropic agent, YS 49, in rat vascular smooth muscle and RAW 264.7 macrophages.

Kang YJ, Koo EB, Lee YS, Yun-Choi HS, Chang KC. Kang YJ, et al. Among authors: chang kc. Br J Pharmacol. 1999 Sep;128(2):357-64. doi: 10.1038/sj.bjp.0702787. Br J Pharmacol. 1999. PMID: 10510445 Free PMC article.

5

Suppression of tumor necrosis factor-alpha and inducible nitric oxide synthase gene expression by THI 52, a new synthetic naphthyl-benzylisoquinoline alkaloid.

Kang YJ, Lee BK, Lee YS, Seo HG, Park MK, Kim HJ, Pyo HS, Chong WS, Jung HJ, Yun-Choi HS, Lee DH, Chang KC. Kang YJ, et al. Among authors: chang kc. Biochem Pharmacol. 2003 Feb 1;65(3):457-64. doi: 10.1016/s0006-2952(02)01549-6. Biochem Pharmacol. 2003. PMID: 12527339

6

Induction of manganese-superoxide dismutase by YS 51, a synthetic 1-(beta-naphtylmethyl)6,7-dihydroxy- 1,2,3,4-tetrahydroisoquinoline alkaloid: implication for anti-inflammatory actions.

Seo HG, Kim HJ, Ko YS, Pyo HS, Kang YJ, Lee YS, Park MK, Yun-Choi HS, Chang KC. Seo HG, et al. Among authors: chang kc. Pharmacology. 2004 Jun;71(2):57-65. doi: 10.1159/000076941. Pharmacology. 2004. PMID: 15118344

7

Regulation of lipopolysaccharide-induced inducible nitric-oxide synthase expression through the nuclear factor-kappaB pathway and interferon-beta/tyrosine kinase 2/Janus tyrosine kinase 2-signal transducer and activator of transcription-1 signaling cascades by 2-naphthylethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (THI 53), a new synthetic isoquinoline alkaloid.

Kim HJ, Tsoyi K, Heo JM, Kang YJ, Park MK, Lee YS, Lee JH, Seo HG, Yun-Choi HS, Chang KC. Kim HJ, et al. Among authors: chang kc. J Pharmacol Exp Ther. 2007 Feb;320(2):782-9. doi: 10.1124/jpet.106.112052. Epub 2006 Nov 15. J Pharmacol Exp Ther. 2007. PMID: 17108235

8

YS 51, 1-(beta-naphtylmethyl)-6,7-dihydroxy-1,2,3,4,-tetrahydroisoquinoline, protects endothelial cells against hydrogen peroxide-induced injury via carbon monoxide derived from heme oxygenase-1.

Heo JM, Kim HJ, Ha YM, Park MK, Kang YJ, Lee YS, Seo HG, Lee JH, Yun-Choi HS, Chang KC. Heo JM, et al. Among authors: chang kc. Biochem Pharmacol. 2007 Nov 1;74(9):1361-70. doi: 10.1016/j.bcp.2007.07.023. Epub 2007 Jul 21. Biochem Pharmacol. 2007. PMID: 17719563

9

(S)-1-(alpha-naphthylmethyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (CKD712) reduces rat myocardial apoptosis against ischemia and reperfusion injury by activation of phosphatidylinositol 3-kinase/Akt signaling and anti-inflammatory action in vivo.

Jin YC, Lee YS, Kim YM, Seo HG, Lee JH, Kim HJ, Yun-Choi HS, Chang KC. Jin YC, et al. Among authors: chang kc. J Pharmacol Exp Ther. 2009 Aug;330(2):440-8. doi: 10.1124/jpet.108.150342. Epub 2009 May 20. J Pharmacol Exp Ther. 2009. PMID: 19458286

10

Upregulation of PTEN by CKD712, a synthetic tetrahydroisoquinoline alkaloid, selectively inhibits lipopolysaccharide-induced VCAM-1 but not ICAM-1 expression in human endothelial cells.

Tsoyi K, Kim WS, Kim YM, Kim HJ, Seo HG, Lee JH, Yun-Choi HS, Chang KC. Tsoyi K, et al. Among authors: chang kc. Atherosclerosis. 2009 Dec;207(2):412-9. doi: 10.1016/j.atherosclerosis.2009.05.012. Epub 2009 May 21. Atherosclerosis. 2009. PMID: 19540498

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