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Low structural specificity for nucleoside triphosphates as antagonists of ADP-induced platelet activation.
Greco NJ, Tandon NN, Jackson BW, Jamieson GA. Greco NJ, et al. Among authors: tandon nn. J Biol Chem. 1992 Feb 15;267(5):2966-70. J Biol Chem. 1992. PMID: 1737752 Free article.
Although the platelet ADP receptor is thought to exhibit a high degree of structural selectivity, adenosine 5'-O-(thiotriphosphate) (ATP alpha S) is a potent inhibitor of ADP-induced platelet activation and has been recently shown to bind with high affinity (Kd 3 +/- 0.1 nM) to f …
Although the platelet ADP receptor is thought to exhibit a high degree of structural selectivity, adenosine 5'-O-(thiotriphosphate) (ATP alp …
1,174 results