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Human cell-adhesion molecule CD2 binds CD58 (LFA-3) with a very low affinity and an extremely fast dissociation rate but does not bind CD48 or CD59.
van der Merwe PA, Barclay AN, Mason DW, Davies EA, Morgan BP, Tone M, Krishnam AK, Ianelli C, Davis SJ. van der Merwe PA, et al. Among authors: barclay an. Biochemistry. 1994 Aug 23;33(33):10149-60. doi: 10.1021/bi00199a043. Biochemistry. 1994. PMID: 7520278
Using surface plasmon resonance technology, which avoids several pitfalls of conventional binding assays, we recently reported that rat CD2 binds rat CD48 with a very low affinity (Kd 60-90 microM) and dissociates rapidly (koff > or = 6 s-1) [van der Merwe, P. A., Brown, M. H. …
Using surface plasmon resonance technology, which avoids several pitfalls of conventional binding assays, we recently reported that rat CD2 …
Analysis of the structure and interactions of CD2.
Davis SJ, Jones EY, Bodian DL, Barclay AN, van der Merwe PA. Davis SJ, et al. Among authors: barclay an. Biochem Soc Trans. 1993 Nov;21(4):952-8. doi: 10.1042/bst0210952. Biochem Soc Trans. 1993. PMID: 7907562 Review. No abstract available.
176 results