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A novel gene delivery method transduces porcine pancreatic duct epithelial cells.
Griffin MA, Restrepo MS, Abu-El-Haija M, Wallen T, Buchanan E, Rokhlina T, Chen YH, McCray PB Jr, Davidson BL, Divekar A, Uc A. Griffin MA, et al. Among authors: rokhlina t. Gene Ther. 2014 Feb;21(2):123-30. doi: 10.1038/gt.2013.62. Epub 2013 Nov 21. Gene Ther. 2014. PMID: 24257348 Free PMC article.
Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs.
Stoltz DA, Rokhlina T, Ernst SE, Pezzulo AA, Ostedgaard LS, Karp PH, Samuel MS, Reznikov LR, Rector MV, Gansemer ND, Bouzek DC, Abou Alaiwa MH, Hoegger MJ, Ludwig PS, Taft PJ, Wallen TJ, Wohlford-Lenane C, McMenimen JD, Chen JH, Bogan KL, Adam RJ, Hornick EE, Nelson GA 4th, Hoffman EA, Chang EH, Zabner J, McCray PB Jr, Prather RS, Meyerholz DK, Welsh MJ. Stoltz DA, et al. Among authors: rokhlina t. J Clin Invest. 2013 Jun;123(6):2685-93. doi: 10.1172/JCI68867. Epub 2013 May 8. J Clin Invest. 2013. PMID: 23676501 Free PMC article.
The ΔF508 mutation causes CFTR misprocessing and cystic fibrosis-like disease in pigs.
Ostedgaard LS, Meyerholz DK, Chen JH, Pezzulo AA, Karp PH, Rokhlina T, Ernst SE, Hanfland RA, Reznikov LR, Ludwig PS, Rogan MP, Davis GJ, Dohrn CL, Wohlford-Lenane C, Taft PJ, Rector MV, Hornick E, Nassar BS, Samuel M, Zhang Y, Richter SS, Uc A, Shilyansky J, Prather RS, McCray PB Jr, Zabner J, Welsh MJ, Stoltz DA. Ostedgaard LS, et al. Among authors: rokhlina t. Sci Transl Med. 2011 Mar 16;3(74):74ra24. doi: 10.1126/scitranslmed.3001868. Sci Transl Med. 2011. PMID: 21411740 Free PMC article.
Cystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth.
Stoltz DA, Meyerholz DK, Pezzulo AA, Ramachandran S, Rogan MP, Davis GJ, Hanfland RA, Wohlford-Lenane C, Dohrn CL, Bartlett JA, Nelson GA 4th, Chang EH, Taft PJ, Ludwig PS, Estin M, Hornick EE, Launspach JL, Samuel M, Rokhlina T, Karp PH, Ostedgaard LS, Uc A, Starner TD, Horswill AR, Brogden KA, Prather RS, Richter SS, Shilyansky J, McCray PB Jr, Zabner J, Welsh MJ. Stoltz DA, et al. Among authors: rokhlina t. Sci Transl Med. 2010 Apr 28;2(29):29ra31. doi: 10.1126/scitranslmed.3000928. Sci Transl Med. 2010. PMID: 20427821 Free PMC article.
20 results