Bowtell D - Search Results

1

B cell antigen receptor cross-linking induces phosphorylation of the p21ras oncoprotein activators SHC and mSOS1 as well as assembly of complexes containing SHC, GRB-2, mSOS1, and a 145-kDa tyrosine-phosphorylated protein.

Saxton TM, van Oostveen I, Bowtell D, Aebersold R, Gold MR. Saxton TM, et al. Among authors: bowtell d. J Immunol. 1994 Jul 15;153(2):623-36. J Immunol. 1994. PMID: 8021500

2

Multiple hemopoietins, with the exception of interleukin-4, induce modification of Shc and mSos1, but not their translocation.

Welham MJ, Duronio V, Leslie KB, Bowtell D, Schrader JW. Welham MJ, et al. Among authors: bowtell d. J Biol Chem. 1994 Aug 19;269(33):21165-76. J Biol Chem. 1994. PMID: 8063737 Free article.

3

Perturbed regulation of ZAP-70 and sustained tyrosine phosphorylation of LAT and SLP-76 in c-Cbl-deficient thymocytes.

Thien CB, Bowtell DD, Langdon WY. Thien CB, et al. Among authors: bowtell dd. J Immunol. 1999 Jun 15;162(12):7133-9. J Immunol. 1999. PMID: 10358158

4

Bcr-Abl oncoproteins bind directly to activators of the Ras signalling pathway.

Puil L, Liu J, Gish G, Mbamalu G, Bowtell D, Pelicci PG, Arlinghaus R, Pawson T. Puil L, et al. Among authors: bowtell d. EMBO J. 1994 Feb 15;13(4):764-73. doi: 10.1002/j.1460-2075.1994.tb06319.x. EMBO J. 1994. PMID: 8112292 Free PMC article.

5

The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1.

Rozakis-Adcock M, Fernley R, Wade J, Pawson T, Bowtell D. Rozakis-Adcock M, et al. Among authors: bowtell d. Nature. 1993 May 6;363(6424):83-5. doi: 10.1038/363083a0. Nature. 1993. PMID: 8479540

6

Shc, Grb2, Sos1, and a 150-kilodalton tyrosine-phosphorylated protein form complexes with Fms in hematopoietic cells.

Lioubin MN, Myles GM, Carlberg K, Bowtell D, Rohrschneider LR. Lioubin MN, et al. Among authors: bowtell d. Mol Cell Biol. 1994 Sep;14(9):5682-91. doi: 10.1128/mcb.14.9.5682-5691.1994. Mol Cell Biol. 1994. PMID: 7520523 Free PMC article.

7

The protein product of the c-cbl oncogene rapidly complexes with the EGF receptor and is tyrosine phosphorylated following EGF stimulation.

Bowtell DD, Langdon WY. Bowtell DD, et al. Oncogene. 1995 Oct 19;11(8):1561-7. Oncogene. 1995. PMID: 7478580

8

Molecular characterization of mucinous ovarian tumours supports a stratified treatment approach with HER2 targeting in 19% of carcinomas.

Anglesio MS, Kommoss S, Tolcher MC, Clarke B, Galletta L, Porter H, Damaraju S, Fereday S, Winterhoff BJ, Kalloger SE, Senz J, Yang W, Steed H, Allo G, Ferguson S, Shaw P, Teoman A, Garcia JJ, Schoolmeester JK, Bakkum-Gamez J, Tinker AV, Bowtell DD, Huntsman DG, Gilks CB, McAlpine JN. Anglesio MS, et al. Among authors: bowtell dd. J Pathol. 2013 Jan;229(1):111-20. doi: 10.1002/path.4088. J Pathol. 2013. PMID: 22899400

9

A dominant-negative mutant of mSOS1 inhibits insulin-induced Ras activation and reveals Ras-dependent and -independent insulin signaling pathways.

Sakaue M, Bowtell D, Kasuga M. Sakaue M, et al. Among authors: bowtell d. Mol Cell Biol. 1995 Jan;15(1):379-88. doi: 10.1128/MCB.15.1.379. Mol Cell Biol. 1995. PMID: 7799946 Free PMC article.

10

Activation of Ras and its downstream extracellular signal-regulated protein kinases by the CDC25 homology domain of mouse Son-of-sevenless 1 (mSos1).

Kim JH, Shirouzu M, Kataoka T, Bowtell D, Yokoyama S. Kim JH, et al. Among authors: bowtell d. Oncogene. 1998 May;16(20):2597-607. doi: 10.1038/sj.onc.1201822. Oncogene. 1998. PMID: 9632136

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