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Piperidine-renin inhibitors compounds with improved physicochemical properties.
Güller R, Binggeli A, Breu V, Bur D, Fischli W, Hirth G, Jenny C, Kansy M, Montavon F, Müller M, Oefner C, Stadler H, Vieira E, Wilhelm M, Wostl W, Märki HP. Güller R, et al. Among authors: muller m. Bioorg Med Chem Lett. 1999 May 17;9(10):1403-8. doi: 10.1016/s0960-894x(99)00196-1. Bioorg Med Chem Lett. 1999. PMID: 10360745
Piperidine renin inhibitors: from leads to drug candidates.
Märki HP, Binggeli A, Bittner B, Bohner-Lang V, Breu V, Bur D, Coassolo PH, Clozel JP, D'Arcy A, Doebeli H, Fischli W, Funk CH, Foricher J, Giller T, Grüninger F, Guenzi A, Güller R, Hartung T, Hirth G, Jenny CH, Kansy M, Klinkhammer U, Lave T, Lohri B, Luft FC, Mervaala EM, Müller DN, Müller M, Montavon F, Oefner CH, Qiu C, Reichel A, Sanwald-Ducray P, Scalone M, Schleimer M, Schmid R, Stadler H, Treiber A, Valdenaire O, Vieira E, Waldmeier P, Wiegand-Chou R, Wilhelm M, Wostl W, Zell M, Zell R. Märki HP, et al. Among authors: muller m, muller dn. Farmaco. 2001 Jan-Feb;56(1-2):21-7. doi: 10.1016/s0014-827x(01)01004-7. Farmaco. 2001. PMID: 11347960
Orally active fibrinogen receptor antagonists. 2. Amidoximes as prodrugs of amidines.
Weller T, Alig L, Beresini M, Blackburn B, Bunting S, Hadváry P, Müller MH, Knopp D, Levet-Trafit B, Lipari MT, Modi NB, Müller M, Refino CJ, Schmitt M, Schönholzer P, Weiss S, Steiner B. Weller T, et al. Among authors: muller m, muller mh. J Med Chem. 1996 Aug 2;39(16):3139-47. doi: 10.1021/jm9509298. J Med Chem. 1996. PMID: 8759635
4,5-Dianilinophthalimide: a protein-tyrosine kinase inhibitor with selectivity for the epidermal growth factor receptor signal transduction pathway and potent in vivo antitumor activity.
Buchdunger E, Trinks U, Mett H, Regenass U, Müller M, Meyer T, McGlynn E, Pinna LA, Traxler P, Lydon NB. Buchdunger E, et al. Among authors: muller m. Proc Natl Acad Sci U S A. 1994 Mar 15;91(6):2334-8. doi: 10.1073/pnas.91.6.2334. Proc Natl Acad Sci U S A. 1994. Retraction in: Proc Natl Acad Sci U S A. 1998 Sep 29;95(20):12069. doi: 10.1073/pnas.95.20.12069-a PMID: 8134396 Free PMC article. Retracted.
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