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Abnormalities of chromosome 1p/q are highly associated with chromosome 13/13q deletions and are an adverse prognostic factor for the outcome of high-dose chemotherapy in patients with multiple myeloma.
Wu KL, Beverloo B, Lokhorst HM, Segeren CM, van der Holt B, Steijaert MM, Westveer PH, Poddighe PJ, Verhoef GE, Sonneveld P; Dutch-Belgian Haemato-Oncology Cooperative Study Group (HOVON); Dutch Working Party on Cancer Genetics and Cytogenetics (NWCGC). Wu KL, et al. Among authors: poddighe pj. Br J Haematol. 2007 Feb;136(4):615-23. doi: 10.1111/j.1365-2141.2006.06481.x. Br J Haematol. 2007. PMID: 17223915 Free article. Clinical Trial.
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