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Structure-function analysis of human IL-6: identification of two distinct regions that are important for receptor binding.
Hammacher A, Ward LD, Weinstock J, Treutlein H, Yasukawa K, Simpson RJ. Hammacher A, et al. Among authors: ward ld. Protein Sci. 1994 Dec;3(12):2280-93. doi: 10.1002/pro.5560031213. Protein Sci. 1994. PMID: 7538847 Free PMC article.
Previously, we demonstrated that the 5 C-terminal residues of mIL-6 are important for activity, conformation, and stability (Ward LD et al., 1993, Protein Sci 2:1472-1481). To further probe the structure-function relationship of this cytokine, we have constructed se …
Previously, we demonstrated that the 5 C-terminal residues of mIL-6 are important for activity, conformation, and stability (Ward
Interleukin-6: structure-function relationships.
Simpson RJ, Hammacher A, Smith DK, Matthews JM, Ward LD. Simpson RJ, et al. Among authors: ward ld. Protein Sci. 1997 May;6(5):929-55. doi: 10.1002/pro.5560060501. Protein Sci. 1997. PMID: 9144766 Free PMC article. Review.
133 results