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Page 1
Muscarinic receptor antagonist-induced lenticular opacity in rats.
Durand G, Hubert MF, Kuno H, Cook WO, Boussiquet-Leroux C, Owen R, Fujimaki Y, Kemi M, Virat M, van Zwieten MJ. Durand G, et al. Among authors: boussiquet leroux c. Toxicol Sci. 2002 Mar;66(1):166-72. doi: 10.1093/toxsci/66.1.166. Toxicol Sci. 2002. PMID: 11861984
The novel gamma secretase inhibitor N-[cis-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoromethanesulfonamide (MRK-560) reduces amyloid plaque deposition without evidence of notch-related pathology in the Tg2576 mouse.
Best JD, Smith DW, Reilly MA, O'Donnell R, Lewis HD, Ellis S, Wilkie N, Rosahl TW, Laroque PA, Boussiquet-Leroux C, Churcher I, Atack JR, Harrison T, Shearman MS. Best JD, et al. Among authors: boussiquet leroux c. J Pharmacol Exp Ther. 2007 Feb;320(2):552-8. doi: 10.1124/jpet.106.114330. Epub 2006 Nov 10. J Pharmacol Exp Ther. 2007. PMID: 17099072