The antimalarial drug, chloroquine, interacts with lactate dehydrogenase from Plasmodium falciparum.
Menting JG, Tilley L, Deady LW, Ng K, Simpson RJ, Cowman AF, Foley M.
Menting JG, et al. Among authors: foley m.
Mol Biochem Parasitol. 1997 Sep;88(1-2):215-24. doi: 10.1016/s0166-6851(97)00095-9.
Mol Biochem Parasitol. 1997.
PMID: 9274881
We have previously shown that a radioiodinated photoreactive analogue of chloroquine, [125I]N-(4-(4-diethylamino-1-methylbutylamino)quinolin-6-yl) -4-azido-2-hydroxybenzamide ([125I]ASA-Q), specifically labels two proteins in Plasmodium falciparum with apparent molecular weights …
We have previously shown that a radioiodinated photoreactive analogue of chloroquine, [125I]N-(4-(4-diethylamino-1-methylbutylamino)quinolin …