Simonet WS - Search Results

1

Sequences containing the second-intron enhancer are essential for transcription of the human apolipoprotein B gene in the livers of transgenic mice.

Brooks AR, Nagy BP, Taylor S, Simonet WS, Taylor JM, Levy-Wilson B. Brooks AR, et al. Among authors: simonet ws. Mol Cell Biol. 1994 Apr;14(4):2243-56. doi: 10.1128/mcb.14.4.2243-2256.1994. Mol Cell Biol. 1994. PMID: 8139530 Free PMC article.

2

A far-downstream hepatocyte-specific control region directs expression of the linked human apolipoprotein E and C-I genes in transgenic mice.

Simonet WS, Bucay N, Lauer SJ, Taylor JM. Simonet WS, et al. J Biol Chem. 1993 Apr 15;268(11):8221-9. J Biol Chem. 1993. PMID: 7681840 Free article.

3

Altered lipoprotein metabolism in transgenic mice expressing low levels of a human receptor-binding-defective apolipoprotein E variant.

Fazio S, Horie Y, Simonet WS, Weisgraber KH, Taylor JM, Rall SC Jr. Fazio S, et al. Among authors: simonet ws. J Lipid Res. 1994 Mar;35(3):408-16. J Lipid Res. 1994. PMID: 8014576 Free article.

4

Multiple tissue-specific elements control the apolipoprotein E/C-I gene locus in transgenic mice.

Simonet WS, Bucay N, Pitas RE, Lauer SJ, Taylor JM. Simonet WS, et al. J Biol Chem. 1991 May 15;266(14):8651-4. J Biol Chem. 1991. PMID: 2026582 Free article.

5

Downstream regulatory elements stimulate expression of the human apolipoprotein E gene in the liver and suppress expression in the kidney of transgenic mice.

Simonet WS, Bucay N, Lauer SJ, Pitas RE, Weisgraber KH, Taylor JM. Simonet WS, et al. Trans Assoc Am Physicians. 1990;103:119-28. Trans Assoc Am Physicians. 1990. PMID: 2132523 Review. No abstract available.

6

In the absence of a downstream element, the apolipoprotein E gene is expressed at high levels in kidneys of transgenic mice.

Simonet WS, Bucay N, Lauer SJ, Wirak DO, Stevens ME, Weisgraber KH, Pitas RE, Taylor JM. Simonet WS, et al. J Biol Chem. 1990 Jul 5;265(19):10809-12. J Biol Chem. 1990. PMID: 2193025 Free article.

7

Overexpression of human apolipoprotein C-III in transgenic mice results in an accumulation of apolipoprotein B48 remnants that is corrected by excess apolipoprotein E.

de Silva HV, Lauer SJ, Wang J, Simonet WS, Weisgraber KH, Mahley RW, Taylor JM. de Silva HV, et al. Among authors: simonet ws. J Biol Chem. 1994 Jan 21;269(3):2324-35. J Biol Chem. 1994. PMID: 8294490 Free article.

8

FGF-18, a novel member of the fibroblast growth factor family, stimulates hepatic and intestinal proliferation.

Hu MC, Qiu WR, Wang YP, Hill D, Ring BD, Scully S, Bolon B, DeRose M, Luethy R, Simonet WS, Arakawa T, Danilenko DM. Hu MC, et al. Among authors: simonet ws. Mol Cell Biol. 1998 Oct;18(10):6063-74. doi: 10.1128/MCB.18.10.6063. Mol Cell Biol. 1998. PMID: 9742123 Free PMC article.

9

Long-term impaired neutrophil migration in mice overexpressing human interleukin-8.

Simonet WS, Hughes TM, Nguyen HQ, Trebasky LD, Danilenko DM, Medlock ES. Simonet WS, et al. J Clin Invest. 1994 Sep;94(3):1310-9. doi: 10.1172/JCI117450. J Clin Invest. 1994. PMID: 7521886 Free PMC article.

10

Expression of keratinocyte growth factor in embryonic liver of transgenic mice causes changes in epithelial growth and differentiation resulting in polycystic kidneys and other organ malformations.

Nguyen HQ, Danilenko DM, Bucay N, DeRose ML, Van GY, Thomason A, Simonet WS. Nguyen HQ, et al. Among authors: simonet ws. Oncogene. 1996 May 16;12(10):2109-19. Oncogene. 1996. PMID: 8668336

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