Stashko MA - Search Results

1

Novel Asp32-replacement tetrapeptide analogues as potent and selective CCK-A agonists.

Elliott RL, Kopecka H, Tufano MD, Shue YK, Gauri AJ, Lin CW, Bianchi BR, Miller TR, Witte DG, Stashko MA, et al. Elliott RL, et al. Among authors: stashko ma. J Med Chem. 1994 May 27;37(11):1562-8. doi: 10.1021/jm00037a005. J Med Chem. 1994. PMID: 8201590

2

Development of potent and selective CCK-A receptor agonists from Boc-CCK-4: tetrapeptides containing Lys(N epsilon)-amide residues.

Shiosaki K, Lin CW, Kopecka H, Craig RA, Bianchi BR, Miller TR, Witte DG, Stashko M, Nadzan AM. Shiosaki K, et al. J Med Chem. 1992 May 29;35(11):2007-14. doi: 10.1021/jm00089a010. J Med Chem. 1992. PMID: 1375964

3

Cholecystokinin antagonists: (R)-tryptophan-based hybrid antagonists of high affinity and selectivity for CCK-A receptors.

Kerwin JF Jr, Wagenaar F, Kopecka H, Lin CW, Miller T, Witte D, Stashko M, Nadzan AM. Kerwin JF Jr, et al. J Med Chem. 1991 Dec;34(12):3350-9. doi: 10.1021/jm00116a002. J Med Chem. 1991. PMID: 1766000

4

Characterization of cloned human dopamine D1 receptor-mediated calcium release in 293 cells.

Lin CW, Miller TR, Witte DG, Bianchi BR, Stashko M, Manelli AM, Frail DE. Lin CW, et al. Mol Pharmacol. 1995 Jan;47(1):131-9. Mol Pharmacol. 1995. PMID: 7838121

5

Double bond isosteres of the peptide bond: synthesis and biological activity of cholecystokinin (CCK) C-terminal hexapeptide analogs.

Shue YK, Tufano MD, Carrera GM Jr, Kopecka H, Kuyper SL, Holladay MW, Lin CW, Witte DG, Miller TR, Stashko M, et al. Shue YK, et al. Bioorg Med Chem. 1993 Sep;1(3):161-71. doi: 10.1016/s0968-0896(00)82117-3. Bioorg Med Chem. 1993. PMID: 8081848

6

CCK-A-selective tetrapeptides containing lys(N epsilon)-amide residues: favorable in vivo and in vitro effects of N-methylation at the aspartyl residue.

Bennett MJ, Nikkel AL, Bianchi BR, Miller TR, Bednarz L, Witte DG, Stashko M, Wang SS, Gore PA, Asin KE, et al. Bennett MJ, et al. J Med Chem. 1994 May 27;37(11):1569-71. doi: 10.1021/jm00037a006. J Med Chem. 1994. PMID: 8201591

7

Tetrapeptide CCK agonists: structure-activity studies on modifications at the N-terminus.

Elliott RL, Kopecka H, Bennett MJ, Shue YK, Craig R, Lin CW, Bianchi BR, Miller TR, Witte DG, Stashko MA, et al. Elliott RL, et al. Among authors: stashko ma. J Med Chem. 1994 Jan 21;37(2):309-13. doi: 10.1021/jm00028a015. J Med Chem. 1994. PMID: 8295219

8

ABT-431: the diacetyl prodrug of A-86929, a potent and selective dopamine D1 receptor agonist: in vitro characterization and effects in animal models of Parkinson's disease.

Shiosaki K, Jenner P, Asin KE, Britton DR, Lin CW, Michaelides M, Smith L, Bianchi B, Didomenico S, Hodges L, Hong Y, Mahan L, Mikusa J, Miller T, Nikkel A, Stashko M, Witte D, Williams M. Shiosaki K, et al. J Pharmacol Exp Ther. 1996 Jan;276(1):150-60. J Pharmacol Exp Ther. 1996. PMID: 8558425

9

Persistent activation of the dopamine D1 receptor contributes to prolonged receptor desensitization: studies with A-77636.

Lin CW, Bianchi BR, Miller TR, Stashko MA, Wang SS, Curzon P, Bednarz L, Asin KE, Britton DR. Lin CW, et al. Among authors: stashko ma. J Pharmacol Exp Ther. 1996 Mar;276(3):1022-9. J Pharmacol Exp Ther. 1996. PMID: 8786531

10

Minor structural differences in Boc-CCK-4 derivatives dictate affinity and selectivity for CCK-A and CCK-B receptors.

Shiosaki K, Lin CW, Kopecka H, Bianchi B, Miller T, Stashko M, Witte D. Shiosaki K, et al. J Med Chem. 1997 Mar 28;40(7):1169-72. doi: 10.1021/jm960509y. J Med Chem. 1997. PMID: 9089338

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