Faust KA - Search Results

1

A potent, orally active, balanced affinity angiotensin II AT1 antagonist and AT2 binding inhibitor.

de Laszlo SE, Quagliato CS, Greenlee WJ, Patchett AA, Chang RS, Lotti VJ, Chen TB, Scheck SA, Faust KA, Kivlighn SS, et al. de Laszlo SE, et al. Among authors: faust ka. J Med Chem. 1993 Oct 15;36(21):3207-10. doi: 10.1021/jm00073a024. J Med Chem. 1993. PMID: 8230109 No abstract available.

2

Potent, orally active imidazo[4,5-b]pyridine-based angiotensin II receptor antagonists.

Mantlo NB, Chakravarty PK, Ondeyka DL, Siegl PK, Chang RS, Lotti VJ, Faust KA, Chen TB, Schorn TW, Sweet CS, et al. Mantlo NB, et al. Among authors: faust ka. J Med Chem. 1991 Sep;34(9):2919-22. doi: 10.1021/jm00113a035. J Med Chem. 1991. PMID: 1895308 No abstract available.

3

A highly potent, orally active imidazo[4,5-b]pyridine biphenylacylsulfonamide (MK-996; L-159,282): a new AT1-selective angiotensin II receptor antagonist.

Chakravarty PK, Naylor EM, Chen A, Chang RS, Chen TB, Faust KA, Lotti VJ, Kivlighn SD, Gable RA, Zingaro GJ, et al. Chakravarty PK, et al. Among authors: faust ka. J Med Chem. 1994 Nov 25;37(24):4068-72. doi: 10.1021/jm00050a002. J Med Chem. 1994. PMID: 7990105 No abstract available.

4

Triazolinone biphenylsulfonamide derivatives as orally active angiotensin II antagonists with potent AT1 receptor affinity and enhanced AT2 affinity.

Ashton WT, Chang LL, Flanagan KL, Hutchins SM, Naylor EM, Chakravarty PK, Patchett AA, Greenlee WJ, Chen TB, Faust KA, et al. Ashton WT, et al. Among authors: faust ka. J Med Chem. 1994 Aug 19;37(17):2808-24. doi: 10.1021/jm00043a020. J Med Chem. 1994. PMID: 8064808

5

Nonpeptide angiotensin II antagonists derived from 1H-pyrazole-5-carboxylates and 4-aryl-1H-imidazole-5-carboxylates.

Ashton WT, Hutchins SM, Greenlee WJ, Doss GA, Chang RS, Lotti VJ, Faust KA, Chen TB, Zingaro GJ, Kivlighn SD, et al. Ashton WT, et al. Among authors: faust ka. J Med Chem. 1993 Nov 12;36(23):3595-605. doi: 10.1021/jm00075a014. J Med Chem. 1993. PMID: 8246227

6

Triazolinones as nonpeptide angiotensin II antagonists. 1. Synthesis and evaluation of potent 2,4,5-trisubstituted triazolinones.

Chang LL, Ashton WT, Flanagan KL, Strelitz RA, MacCoss M, Greenlee WJ, Chang RS, Lotti VJ, Faust KA, Chen TB, et al. Chang LL, et al. Among authors: faust ka. J Med Chem. 1993 Aug 20;36(17):2558-68. doi: 10.1021/jm00069a015. J Med Chem. 1993. PMID: 8355255

7

Nonpeptide angiotensin II antagonists derived from 4H-1,2,4-triazoles and 3H-imidazo[1,2-b][1,2,4]triazoles.

Ashton WT, Cantone CL, Chang LL, Hutchins SM, Strelitz RA, MacCoss M, Chang RS, Lotti VJ, Faust KA, Chen TB, et al. Ashton WT, et al. Among authors: faust ka. J Med Chem. 1993 Mar 5;36(5):591-609. doi: 10.1021/jm00057a009. J Med Chem. 1993. PMID: 8496939

8

Two angiotensin II binding sites in rat brain revealed using [125I]Sar1, Ile8-angiotensin II and selective nonpeptide antagonists.

Chang RS, Lotti VJ, Chen TB, Faust KA. Chang RS, et al. Among authors: faust ka. Biochem Biophys Res Commun. 1990 Sep 14;171(2):813-7. doi: 10.1016/0006-291x(90)91218-h. Biochem Biophys Res Commun. 1990. PMID: 2403363

9

Novel and potent gastrin and brain cholecystokinin antagonists from Streptomyces olivaceus. Taxonomy, fermentation, isolation, chemical conversions, and physico-chemical and biochemical properties.

Lam YK, Bogen D, Chang RS, Faust KA, Hensens OD, Zink DL, Schwartz CD, Zitano L, Garrity GM, Gagliardi MM, et al. Lam YK, et al. Among authors: faust ka. J Antibiot (Tokyo). 1991 Jun;44(6):613-25. doi: 10.7164/antibiotics.44.613. J Antibiot (Tokyo). 1991. PMID: 1906451 Free article.

10

Rivaroxaban or aspirin for patent foramen ovale and embolic stroke of undetermined source: a prespecified subgroup analysis from the NAVIGATE ESUS trial.

Kasner SE, Swaminathan B, Lavados P, Sharma M, Muir K, Veltkamp R, Ameriso SF, Endres M, Lutsep H, Messé SR, Spence JD, Nedeltechev K, Perera K, Santo G, Olavarria V, Lindgren A, Bangdiwala S, Shoamanesh A, Berkowitz SD, Mundl H, Connolly SJ, Hart RG; NAVIGATE ESUS Investigators. Kasner SE, et al. Lancet Neurol. 2018 Dec;17(12):1053-1060. doi: 10.1016/S1474-4422(18)30319-3. Epub 2018 Sep 28. Lancet Neurol. 2018. PMID: 30274772 Free PMC article. Clinical Trial.

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