Heasley LE - Search Results

1

Expression of a mutant Gi2 alpha subunit inhibits ATP and thrombin stimulation of cytoplasmic phospholipase A2-mediated arachidonic acid release independent of Ca2+ and mitogen-activated protein kinase regulation.

Winitz S, Gupta SK, Qian NX, Heasley LE, Nemenoff RA, Johnson GL. Winitz S, et al. Among authors: heasley le. J Biol Chem. 1994 Jan 21;269(3):1889-95. J Biol Chem. 1994. PMID: 8294438 Free article.

2

MAP kinase is constitutively activated in gip2 and src transformed rat 1a fibroblasts.

Gupta SK, Gallego C, Johnson GL, Heasley LE. Gupta SK, et al. Among authors: heasley le. J Biol Chem. 1992 Apr 25;267(12):7987-90. J Biol Chem. 1992. PMID: 1314814 Free article.

3

The beta-PDGF receptor induces neuronal differentiation of PC12 cells.

Heasley LE, Johnson GL. Heasley LE, et al. Mol Biol Cell. 1992 May;3(5):545-53. doi: 10.1091/mbc.3.5.545. Mol Biol Cell. 1992. PMID: 1319243 Free PMC article.

4

Mitogen-activated protein kinase activation resulting from selective oncogene expression in NIH 3T3 and rat 1a cells.

Gallego C, Gupta SK, Heasley LE, Qian NX, Johnson GL. Gallego C, et al. Among authors: heasley le. Proc Natl Acad Sci U S A. 1992 Aug 15;89(16):7355-9. doi: 10.1073/pnas.89.16.7355. Proc Natl Acad Sci U S A. 1992. PMID: 1323832 Free PMC article.

5

Activating transcription factor-2 DNA-binding activity is stimulated by phosphorylation catalyzed by p42 and p54 microtubule-associated protein kinases.

Abdel-Hafiz HA, Heasley LE, Kyriakis JM, Avruch J, Kroll DJ, Johnson GL, Hoeffler JP. Abdel-Hafiz HA, et al. Among authors: heasley le. Mol Endocrinol. 1992 Dec;6(12):2079-89. doi: 10.1210/mend.6.12.1337144. Mol Endocrinol. 1992. PMID: 1337144

6

Activating mutations in the NH2- and COOH-terminal moieties of the Gs alpha subunit have dominant phenotypes and distinguishable kinetics of adenylyl cyclase stimulation.

Gupta SK, Dhanasekaran N, Heasley LE, Johnson GL. Gupta SK, et al. Among authors: heasley le. J Cell Biochem. 1991 Dec;47(4):359-68. doi: 10.1002/jcb.240470410. J Cell Biochem. 1991. PMID: 1665495

7

Mutation of the Gs protein alpha subunit NH2 terminus relieves an attenuator function, resulting in constitutive adenylyl cyclase stimulation.

Osawa S, Heasley LE, Dhanasekaran N, Gupta SK, Woon CW, Berlot C, Johnson GL. Osawa S, et al. Among authors: heasley le. Mol Cell Biol. 1990 Jun;10(6):2931-40. doi: 10.1128/mcb.10.6.2931-2940.1990. Mol Cell Biol. 1990. PMID: 1692962 Free PMC article.

8

Requirement of the adenovirus E1A transformation domain 1 for inhibition of PC12 cell neuronal differentiation.

Heasley LE, Benedict S, Gleavy J, Johnson GL. Heasley LE, et al. Cell Regul. 1991 Jun;2(6):479-89. doi: 10.1091/mbc.2.6.479. Cell Regul. 1991. PMID: 1832020 Free PMC article.

9

Chimeras of the Gs alpha subunit that had the NH2- or COOH-terminal sequence substituted for the corresponding region of the Gi alpha subunit constitutively activate adenylyl cyclase.

Heasley LE, Dhanasekaran N, Gupta SK, Osawa S, Johnson GL. Heasley LE, et al. Soc Gen Physiol Ser. 1990;45:117-24. Soc Gen Physiol Ser. 1990. PMID: 2165634 No abstract available.

10

A G protein mutant that inhibits thrombin and purinergic receptor activation of phospholipase A2.

Gupta SK, Diez E, Heasley LE, Osawa S, Johnson GL. Gupta SK, et al. Among authors: heasley le. Science. 1990 Aug 10;249(4969):662-6. doi: 10.1126/science.2166341. Science. 1990. PMID: 2166341

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