De Clercq E - Search Results

1

Mechanism of action of acyclic nucleoside phosphonates against herpes virus replication.

Neyts J, De Clercq E. Neyts J, et al. Among authors: de clercq e. Biochem Pharmacol. 1994 Jan 13;47(1):39-41. doi: 10.1016/0006-2952(94)90435-9. Biochem Pharmacol. 1994. PMID: 8311844

2

Antiviral activity of anti-cytomegalovirus agents (HPMPC, HPMPA) assessed by a flow cytometric method and DNA hybridization technique.

Snoeck R, Schols D, Andrei G, Neyts J, De Clercq E. Snoeck R, et al. Among authors: de clercq e. Antiviral Res. 1991 Jul;16(1):1-9. doi: 10.1016/0166-3542(91)90053-t. Antiviral Res. 1991. PMID: 1663725

3

Particular characteristics of the anti-human cytomegalovirus activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) in vitro.

Neyts J, Snoeck R, Balzarini J, De Clercq E. Neyts J, et al. Among authors: de clercq e. Antiviral Res. 1991 Jul;16(1):41-52. doi: 10.1016/0166-3542(91)90057-x. Antiviral Res. 1991. PMID: 1663729

4

Selective inhibition of human cytomegalovirus DNA synthesis by (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine [(S)-HPMPC] and 9-(1,3-dihydroxy-2-propoxymethyl)guanine (DHPG).

Neyts J, Snoeck R, Schols D, Balzarini J, De Clercq E. Neyts J, et al. Among authors: de clercq e. Virology. 1990 Nov;179(1):41-50. doi: 10.1016/0042-6822(90)90271-r. Virology. 1990. PMID: 2171213

5

The N-7-substituted acyclic nucleoside analog 2-amino-7-[(1,3-dihydroxy-2-propoxy)methyl]purine is a potent and selective inhibitor of herpesvirus replication.

Neyts J, Andrei G, Snoeck R, Jähne G, Winkler I, Helsberg M, Balzarini J, De Clercq E. Neyts J, et al. Among authors: de clercq e. Antimicrob Agents Chemother. 1994 Dec;38(12):2710-6. doi: 10.1128/AAC.38.12.2710. Antimicrob Agents Chemother. 1994. PMID: 7695251 Free PMC article.

6

New inhibitors of cytomegalovirus replication: in vitro evaluation, mechanism of action, and in vivo activity.

Neyts J, De Clercq E. Neyts J, et al. Among authors: de clercq e. Verh K Acad Geneeskd Belg. 1994;56(6):561-92. Verh K Acad Geneeskd Belg. 1994. PMID: 7892749

7

Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine for the treatment of lethal vaccinia virus infections in severe combined immune deficiency (SCID) mice.

Neyts J, De Clercq E. Neyts J, et al. Among authors: de clercq e. J Med Virol. 1993 Nov;41(3):242-6. doi: 10.1002/jmv.1890410312. J Med Virol. 1993. PMID: 8263505

8

Activity of the anti-HIV agent 9-(2-phosphonyl-methoxyethyl)-2,6-diaminopurine against cytomegalovirus in vitro and in vivo.

Neyts J, Stals F, Bruggeman C, De Clercq E. Neyts J, et al. Among authors: de clercq e. Eur J Clin Microbiol Infect Dis. 1993 Jun;12(6):437-46. doi: 10.1007/BF01967438. Eur J Clin Microbiol Infect Dis. 1993. PMID: 8395382

9

Antiviral drug susceptibility of human herpesvirus 8.

Neyts J, De Clercq E. Neyts J, et al. Among authors: de clercq e. Antimicrob Agents Chemother. 1997 Dec;41(12):2754-6. doi: 10.1128/AAC.41.12.2754. Antimicrob Agents Chemother. 1997. PMID: 9420052 Free PMC article.

10

Intracellular metabolism of the N7-substituted acyclic nucleoside analog 2-amino-7-(1,3-dihydroxy-2-propoxymethyl)purine, a potent inhibitor of herpesvirus replication.

Neyts J, Balzarini J, Andrei G, Chaoyong Z, Snoeck R, Zimmermann A, Mertens T, Karlsson A, De Clercq E. Neyts J, et al. Among authors: de clercq e. Mol Pharmacol. 1998 Jan;53(1):157-65. doi: 10.1124/mol.53.1.157. Mol Pharmacol. 1998. PMID: 9443944

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