Ruf W - Search Results

1

Mutational mapping of functional residues in tissue factor: identification of factor VII recognition determinants in both structural modules of the predicted cytokine receptor homology domain.

Ruf W, Schullek JR, Stone MJ, Edgington TS. Ruf W, et al. Biochemistry. 1994 Feb 15;33(6):1565-72. doi: 10.1021/bi00172a037. Biochemistry. 1994. PMID: 8312277

2

Cellular immune and cytokine pathways resulting in tissue factor expression and relevance to septic shock.

Edgington TS, Mackman N, Fan ST, Ruf W. Edgington TS, et al. Among authors: ruf w. Nouv Rev Fr Hematol (1978). 1992;34 Suppl:S15-27. Nouv Rev Fr Hematol (1978). 1992. PMID: 1364116 Review.

3

Cofactor residues lysine 165 and 166 are critical for protein substrate recognition by the tissue factor-factor VIIa protease complex.

Ruf W, Miles DJ, Rehemtulla A, Edgington TS. Ruf W, et al. J Biol Chem. 1992 Mar 25;267(9):6375-81. J Biol Chem. 1992. PMID: 1372908 Free article.

4

Tissue factor residues 157-167 are required for efficient proteolytic activation of factor X and factor VII.

Ruf W, Miles DJ, Rehemtulla A, Edgington TS. Ruf W, et al. J Biol Chem. 1992 Nov 5;267(31):22206-10. J Biol Chem. 1992. PMID: 1429572 Free article.

5

Expression of tissue factor by melanoma cells promotes efficient hematogenous metastasis.

Mueller BM, Reisfeld RA, Edgington TS, Ruf W. Mueller BM, et al. Among authors: ruf w. Proc Natl Acad Sci U S A. 1992 Dec 15;89(24):11832-6. doi: 10.1073/pnas.89.24.11832. Proc Natl Acad Sci U S A. 1992. PMID: 1465406 Free PMC article.

6

The third Trp-Lys-Ser (WKS) tripeptide motif in tissue factor is associated with a function site.

Rehemtulla A, Ruf W, Miles DJ, Edgington TS. Rehemtulla A, et al. Among authors: ruf w. Biochem J. 1992 Mar 15;282 ( Pt 3)(Pt 3):737-40. doi: 10.1042/bj2820737. Biochem J. 1992. PMID: 1554354 Free PMC article.

7

Antibody mapping of tissue factor implicates two different exon-encoded regions in function.

Ruf W, Rehemtulla A, Edgington TS. Ruf W, et al. Biochem J. 1991 Sep 15;278 ( Pt 3)(Pt 3):729-33. doi: 10.1042/bj2780729. Biochem J. 1991. PMID: 1716883 Free PMC article.

8

An anti-tissue factor monoclonal antibody which inhibits TF.VIIa complex is a potent anticoagulant in plasma.

Ruf W, Edgington TS. Ruf W, et al. Thromb Haemost. 1991 Nov 1;66(5):529-33. Thromb Haemost. 1991. PMID: 1803616

9

The structural biology of expression and function of tissue factor.

Edgington TS, Mackman N, Brand K, Ruf W. Edgington TS, et al. Among authors: ruf w. Thromb Haemost. 1991 Jul 12;66(1):67-79. Thromb Haemost. 1991. PMID: 1833852 Review.

10

Characterization of factor VII association with tissue factor in solution. High and low affinity calcium binding sites in factor VII contribute to functionally distinct interactions.

Ruf W, Kalnik MW, Lund-Hansen T, Edgington TS. Ruf W, et al. J Biol Chem. 1991 Aug 25;266(24):15719-25. J Biol Chem. 1991. PMID: 1874730 Free article.

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