Kedzie KM - Search Results

1

Cloning, sequencing, and functional studies of phenobarbital-inducible forms of cytochrome P450 2B and 4B expressed in rabbit kidney.

Ryan R, Grimm SW, Kedzie KM, Halpert JR, Philpot RM. Ryan R, et al. Among authors: kedzie km. Arch Biochem Biophys. 1993 Aug 1;304(2):454-63. doi: 10.1006/abbi.1993.1375. Arch Biochem Biophys. 1993. PMID: 8346920

2

Role of residue 478 as a determinant of the substrate specificity of cytochrome P450 2B1.

He YA, Balfour CA, Kedzie KM, Halpert JR. He YA, et al. Among authors: kedzie km. Biochemistry. 1992 Sep 29;31(38):9220-6. doi: 10.1021/bi00153a015. Biochemistry. 1992. PMID: 1390709

3

Functional expression of mammalian cytochromes P450IIB in the yeast Saccharomyces cerevisiae.

Kedzie KM, Philpot RM, Halpert JR. Kedzie KM, et al. Arch Biochem Biophys. 1991 Nov 15;291(1):176-86. doi: 10.1016/0003-9861(91)90121-x. Arch Biochem Biophys. 1991. PMID: 1929429

4

Elucidation of amino acid residues critical for unique activities of rabbit cytochrome P450 2B5 using hybrid enzymes and reciprocal site-directed mutagenesis with rabbit cytochrome P450 2B4.

Szklarz GD, He YQ, Kedzie KM, Halpert JR, Burnett VL. Szklarz GD, et al. Among authors: kedzie km. Arch Biochem Biophys. 1996 Mar 15;327(2):308-18. doi: 10.1006/abbi.1996.0127. Arch Biochem Biophys. 1996. PMID: 8619620

5

Molecular basis for a functionally unique cytochrome P450IIB1 variant.

Kedzie KM, Balfour CA, Escobar GY, Grimm SW, He YA, Pepperl DJ, Regan JW, Stevens JC, Halpert JR. Kedzie KM, et al. J Biol Chem. 1991 Nov 25;266(33):22515-21. J Biol Chem. 1991. PMID: 1718996 Free article.

6

Site-directed mutagenesis of putative substrate recognition sites in cytochrome P450 2B11: importance of amino acid residues 114, 290, and 363 for substrate specificity.

Hasler JA, Harlow GR, Szklarz GD, John GH, Kedzie KM, Burnett VL, He YA, Kaminsky LS, Halpert JR. Hasler JA, et al. Among authors: kedzie km. Mol Pharmacol. 1994 Aug;46(2):338-45. Mol Pharmacol. 1994. PMID: 8078495

7

Hybrid enzymes for structure-function analysis of cytochrome P-450 2B11.

Kedzie KM, Grimm SW, Chen F, Halpert JR. Kedzie KM, et al. Biochim Biophys Acta. 1993 Jul 10;1164(2):124-32. doi: 10.1016/0167-4838(93)90238-m. Biochim Biophys Acta. 1993. PMID: 8329443

8

Molecular cloning and expression of human EP3 receptors: evidence of three variants with differing carboxyl termini.

Regan JW, Bailey TJ, Donello JE, Pierce KL, Pepperl DJ, Zhang D, Kedzie KM, Fairbairn CE, Bogardus AM, Woodward DF, et al. Regan JW, et al. Among authors: kedzie km. Br J Pharmacol. 1994 Jun;112(2):377-85. doi: 10.1111/j.1476-5381.1994.tb13082.x. Br J Pharmacol. 1994. PMID: 8075855 Free PMC article.

9

Cloning of a novel human prostaglandin receptor with characteristics of the pharmacologically defined EP2 subtype.

Regan JW, Bailey TJ, Pepperl DJ, Pierce KL, Bogardus AM, Donello JE, Fairbairn CE, Kedzie KM, Woodward DF, Gil DW. Regan JW, et al. Among authors: kedzie km. Mol Pharmacol. 1994 Aug;46(2):213-20. Mol Pharmacol. 1994. PMID: 8078484

10

A single amino-acid substitution in the EP2 prostaglandin receptor confers responsiveness to prostacyclin analogs.

Kedzie KM, Donello JE, Krauss HA, Regan JW, Gil DW. Kedzie KM, et al. Mol Pharmacol. 1998 Sep;54(3):584-90. doi: 10.1124/mol.54.3.584. Mol Pharmacol. 1998. PMID: 9730918

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