Chen TB - Search Results

1

Triazolinones as nonpeptide angiotensin II antagonists. 1. Synthesis and evaluation of potent 2,4,5-trisubstituted triazolinones.

Chang LL, Ashton WT, Flanagan KL, Strelitz RA, MacCoss M, Greenlee WJ, Chang RS, Lotti VJ, Faust KA, Chen TB, et al. Chang LL, et al. Among authors: chen tb. J Med Chem. 1993 Aug 20;36(17):2558-68. doi: 10.1021/jm00069a015. J Med Chem. 1993. PMID: 8355255

2

Characterization of the binding of [3H]L-158,809: a new potent and selective nonpeptide angiotensin II receptor (AT1) antagonist radioligand.

Chen TB, Lotti VJ, Chang RS. Chen TB, et al. Mol Pharmacol. 1992 Dec;42(6):1077-82. Mol Pharmacol. 1992. PMID: 1480133

3

Potent, orally active imidazo[4,5-b]pyridine-based angiotensin II receptor antagonists.

Mantlo NB, Chakravarty PK, Ondeyka DL, Siegl PK, Chang RS, Lotti VJ, Faust KA, Chen TB, Schorn TW, Sweet CS, et al. Mantlo NB, et al. Among authors: chen tb. J Med Chem. 1991 Sep;34(9):2919-22. doi: 10.1021/jm00113a035. J Med Chem. 1991. PMID: 1895308 No abstract available.

4

Cholecystokinin-A receptor ligands based on the kappa-opioid agonist tifluadom.

Bock MG, DiPardo RM, Evans BE, Rittle KE, Whitter WL, Veber DF, Freidinger RM, Chang RS, Chen TB, Lotti VJ. Bock MG, et al. Among authors: chen tb. J Med Chem. 1990 Jan;33(1):450-5. doi: 10.1021/jm00163a069. J Med Chem. 1990. PMID: 2153212

5

Cholecystokinin antagonists. Synthesis of asperlicin analogues with improved potency and water solubility.

Bock MG, DiPardo RM, Rittle KE, Evans BE, Freidinger RM, Veber DF, Chang RS, Chen TB, Keegan ME, Lotti VJ. Bock MG, et al. Among authors: chen tb. J Med Chem. 1986 Oct;29(10):1941-5. doi: 10.1021/jm00160a024. J Med Chem. 1986. PMID: 3761313

6

Potent and orally active angiotensin II receptor antagonists with equal affinity for human AT1 and AT2 subtypes.

Chang LL, Ashton WT, Flanagan KL, Chen TB, O'Malley SS, Zingaro GJ, Kivlighn SD, Siegl PK, Lotti VJ, Chang RS, et al. Chang LL, et al. Among authors: chen tb. J Med Chem. 1995 Sep 15;38(19):3741-58. doi: 10.1021/jm00019a004. J Med Chem. 1995. PMID: 7562905

7

Triazolinone biphenylsulfonamides as angiotensin II receptor antagonists with high affinity for both the AT1 and AT2 subtypes.

Chang LL, Ashton WT, Flanagan KL, Chen TB, O'Malley SS, Zingaro GJ, Siegl PK, Kivlighn SD, Lotti VJ, Chang RS, et al. Chang LL, et al. Among authors: chen tb. J Med Chem. 1994 Dec 23;37(26):4464-78. doi: 10.1021/jm00052a006. J Med Chem. 1994. PMID: 7799397

8

A highly potent, orally active imidazo[4,5-b]pyridine biphenylacylsulfonamide (MK-996; L-159,282): a new AT1-selective angiotensin II receptor antagonist.

Chakravarty PK, Naylor EM, Chen A, Chang RS, Chen TB, Faust KA, Lotti VJ, Kivlighn SD, Gable RA, Zingaro GJ, et al. Chakravarty PK, et al. Among authors: chen tb, chen a. J Med Chem. 1994 Nov 25;37(24):4068-72. doi: 10.1021/jm00050a002. J Med Chem. 1994. PMID: 7990105 No abstract available.

9

Triazolinone biphenylsulfonamide derivatives as orally active angiotensin II antagonists with potent AT1 receptor affinity and enhanced AT2 affinity.

Ashton WT, Chang LL, Flanagan KL, Hutchins SM, Naylor EM, Chakravarty PK, Patchett AA, Greenlee WJ, Chen TB, Faust KA, et al. Ashton WT, et al. Among authors: chen tb. J Med Chem. 1994 Aug 19;37(17):2808-24. doi: 10.1021/jm00043a020. J Med Chem. 1994. PMID: 8064808

10

A potent, orally active, balanced affinity angiotensin II AT1 antagonist and AT2 binding inhibitor.

de Laszlo SE, Quagliato CS, Greenlee WJ, Patchett AA, Chang RS, Lotti VJ, Chen TB, Scheck SA, Faust KA, Kivlighn SS, et al. de Laszlo SE, et al. Among authors: chen tb. J Med Chem. 1993 Oct 15;36(21):3207-10. doi: 10.1021/jm00073a024. J Med Chem. 1993. PMID: 8230109 No abstract available.

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