Epner EM - Search Results

1

An "in-out" strategy using gene targeting and FLP recombinase for the functional dissection of complex DNA regulatory elements: analysis of the beta-globin locus control region.

Fiering S, Kim CG, Epner EM, Groudine M. Fiering S, et al. Among authors: epner em. Proc Natl Acad Sci U S A. 1993 Sep 15;90(18):8469-73. doi: 10.1073/pnas.90.18.8469. Proc Natl Acad Sci U S A. 1993. PMID: 8378321 Free PMC article.

2

Inactivation of the human beta-globin gene by targeted insertion into the beta-globin locus control region.

Kim CG, Epner EM, Forrester WC, Groudine M. Kim CG, et al. Among authors: epner em. Genes Dev. 1992 Jun;6(6):928-38. doi: 10.1101/gad.6.6.928. Genes Dev. 1992. PMID: 1592262 Free article.

3

Efficient modification of human chromosomal alleles using recombination-proficient chicken/human microcell hybrids.

Dieken ES, Epner EM, Fiering S, Fournier RE, Groudine M. Dieken ES, et al. Among authors: epner em. Nat Genet. 1996 Feb;12(2):174-82. doi: 10.1038/ng0296-174. Nat Genet. 1996. PMID: 8563756

4

Long-distance control of origin choice and replication timing in the human beta-globin locus are independent of the locus control region.

Cimbora DM, Schübeler D, Reik A, Hamilton J, Francastel C, Epner EM, Groudine M. Cimbora DM, et al. Among authors: epner em. Mol Cell Biol. 2000 Aug;20(15):5581-91. doi: 10.1128/MCB.20.15.5581-5591.2000. Mol Cell Biol. 2000. PMID: 10891496 Free PMC article.

5

A deletion of the human beta-globin locus activation region causes a major alteration in chromatin structure and replication across the entire beta-globin locus.

Forrester WC, Epner E, Driscoll MC, Enver T, Brice M, Papayannopoulou T, Groudine M. Forrester WC, et al. Genes Dev. 1990 Oct;4(10):1637-49. doi: 10.1101/gad.4.10.1637. Genes Dev. 1990. PMID: 2249769 Free article.

6

Replication and activation of the human beta-globin gene domain.

Groudine M, Forrester WC, Novak U, Epner E. Groudine M, et al. Prog Clin Biol Res. 1989;316A:15-35. Prog Clin Biol Res. 1989. PMID: 2687889 Review. No abstract available.

7

Asynchronous DNA replication within the human beta-globin gene locus.

Epner E, Forrester WC, Groudine M. Epner E, et al. Proc Natl Acad Sci U S A. 1988 Nov;85(21):8081-5. doi: 10.1073/pnas.85.21.8081. Proc Natl Acad Sci U S A. 1988. PMID: 3186709 Free PMC article.

8

Targeted deletion of 5'HS2 of the murine beta-globin LCR reveals that it is not essential for proper regulation of the beta-globin locus.

Fiering S, Epner E, Robinson K, Zhuang Y, Telling A, Hu M, Martin DI, Enver T, Ley TJ, Groudine M. Fiering S, et al. Genes Dev. 1995 Sep 15;9(18):2203-13. doi: 10.1101/gad.9.18.2203. Genes Dev. 1995. PMID: 7557375 Free article.

9

The locus control region is necessary for gene expression in the human beta-globin locus but not the maintenance of an open chromatin structure in erythroid cells.

Reik A, Telling A, Zitnik G, Cimbora D, Epner E, Groudine M. Reik A, et al. Mol Cell Biol. 1998 Oct;18(10):5992-6000. doi: 10.1128/MCB.18.10.5992. Mol Cell Biol. 1998. PMID: 9742116 Free PMC article.

10

The beta-globin LCR is not necessary for an open chromatin structure or developmentally regulated transcription of the native mouse beta-globin locus.

Epner E, Reik A, Cimbora D, Telling A, Bender MA, Fiering S, Enver T, Martin DI, Kennedy M, Keller G, Groudine M. Epner E, et al. Mol Cell. 1998 Oct;2(4):447-55. doi: 10.1016/s1097-2765(00)80144-6. Mol Cell. 1998. PMID: 9809066 Free article.

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