Sequence analysis of two temperature-sensitive mutations in the alpha subunit gene (rpoA) of Escherichia coli RNA polymerase.
Igarashi K, Fujita N, Ishihama A.
Igarashi K, et al. Among authors: ishihama a.
Nucleic Acids Res. 1990 Oct 25;18(20):5945-8. doi: 10.1093/nar/18.20.5945.
Nucleic Acids Res. 1990.
PMID: 2235479
Free PMC article.
Two mutant alleles, rpoA101 and rpoA112, both of which produce RNA polymerase with altered thermostability and reduced fidelity of transcription in vitro (Ishihama et al. (1980) J. Mol. Biol. 137, 137-150), have been analyzed in details. The mutations were found to be resp …
Two mutant alleles, rpoA101 and rpoA112, both of which produce RNA polymerase with altered thermostability and reduced fidelity of transcrip …