Winn M - Search Results

1

2-(Alkylamino)nicotinic acid and analogs. Potent angiotensin II antagonists.

Winn M, De B, Zydowsky TM, Altenbach RJ, Basha FZ, Boyd SA, Brune ME, Buckner SA, Crowell D, Drizin I, et al. Winn M, et al. J Med Chem. 1993 Sep 3;36(18):2676-88. doi: 10.1021/jm00070a012. J Med Chem. 1993. PMID: 8410980

2

Cardiovascular effects of orally administered ABBOTT-81988, an angiotensin II antagonist, in conscious spontaneously hypertensive rats.

Lee JY, Warner RB, Brune ME, Adler AL, Winn M, De B, Zydowsky TM, Opgenorth TJ, Kerkman DJ, DeBernardis JF. Lee JY, et al. Among authors: winn m. Am J Hypertens. 1994 Nov;7(11):975-83. doi: 10.1093/ajh/7.11.975. Am J Hypertens. 1994. PMID: 7848624

3

Receptor interactions of Abbott-81988, a highly potent, non-peptide angiotensin-II antagonist selective for type-1 receptors.

Hancock AA, Buckner SA, Lee JY, Brune M, Morse PA, Oheim K, Warner RB, Winn M, Zydowsky TM, De B, et al. Hancock AA, et al. Among authors: winn m. J Recept Res. 1994 May;14(3-4):229-49. doi: 10.3109/10799899409066034. J Recept Res. 1994. PMID: 8083867

4

Characterization of antihypertensive activity of ABBOTT-81988, a nonpeptide angiotensin II antagonist in the renal hypertensive rat.

Lee JY, Buckner SA, Brune ME, Warner RB, Winn M, De B, Zydowsky TM, Opgenorth TJ, Kerkman DJ, Debernardis JF. Lee JY, et al. Among authors: winn m. J Pharmacol Exp Ther. 1994 Jan;268(1):427-33. J Pharmacol Exp Ther. 1994. PMID: 8301584

5

Pharmacological characterization of Abbott-81282, a novel, non-peptide angiotensin-II antagonist selective for type-1 receptors.

Hancock AA, Buckner SA, Lee JY, Brune M, Morse PA, Oheim K, Warner RB, Winn M, Zydowsky TM, De B, et al. Hancock AA, et al. Among authors: winn m. Life Sci. 1993;53(11):929-37. doi: 10.1016/0024-3205(93)90445-9. Life Sci. 1993. PMID: 8366760

6

Antihypertensive activity of ABBOTT-81282, a nonpeptide angiotensin II antagonist, in the renal hypertensive rat.

Lee JY, Brune ME, Warner RB, Buckner SB, Winn M, De B, Zydowsky TM, Opgenorth TJ, Kerkman DJ, DeBernardis JF. Lee JY, et al. Among authors: winn m. Pharmacology. 1993 Sep;47(3):176-87. doi: 10.1159/000139095. Pharmacology. 1993. PMID: 8415868

7

2,4-Diarylpyrrolidine-3-carboxylic acids--potent ETA selective endothelin receptor antagonists. 1. Discovery of A-127722.

Winn M, von Geldern TW, Opgenorth TJ, Jae HS, Tasker AS, Boyd SA, Kester JA, Mantei RA, Bal R, Sorensen BK, Wu-Wong JR, Chiou WJ, Dixon DB, Novosad EI, Hernandez L, Marsh KC. Winn M, et al. J Med Chem. 1996 Mar 1;39(5):1039-48. doi: 10.1021/jm9505369. J Med Chem. 1996. PMID: 8676339

8

Pyrrolidine-3-carboxylic acids as endothelin antagonists. 3. Discovery of a potent, 2-nonaryl, highly selective ETA antagonist (A-216546).

Liu G, Henry KJ Jr, Szczepankiewicz BG, Winn M, Kozmina NS, Boyd SA, Wasicak J, von Geldern TW, Wu-Wong JR, Chiou WJ, Dixon DB, Nguyen B, Marsh KC, Opgenorth TJ. Liu G, et al. Among authors: winn m. J Med Chem. 1998 Aug 13;41(17):3261-75. doi: 10.1021/jm980217s. J Med Chem. 1998. PMID: 9703472

9

Discovery of a novel class of orally active, non-peptide angiotensin II antagonists.

De B, Winn M, Zydowsky TM, Kerkman DJ, DeBernardis JF, Lee J, Buckner S, Warner R, Brune M, Hancock A, et al. De B, et al. Among authors: winn m. J Med Chem. 1992 Oct 2;35(20):3714-7. doi: 10.1021/jm00098a018. J Med Chem. 1992. PMID: 1433184 No abstract available.

10

Discovery of a series of pyrrolidine-based endothelin receptor antagonists with enhanced ET(A) receptor selectivity.

Boyd SA, Mantei RA, Tasker AS, Liu G, Sorensen BK, Henry KJ Jr, von Geldern TW, Winn M, Wu-Wong JR, Chiou WJ, Dixon DB, Hutchins CW, Marsh KC, Nguyen B, Opgenorth TJ. Boyd SA, et al. Among authors: winn m. Bioorg Med Chem. 1999 Jun;7(6):991-1002. doi: 10.1016/s0968-0896(99)00022-x. Bioorg Med Chem. 1999. PMID: 10428367

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