Leander JD - Search Results

1

Structure-activity relationships of trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidine antagonists for mu- and kappa-opioid receptors.

Zimmerman DM, Leander JD, Cantrell BE, Reel JK, Snoddy J, Mendelsohn LG, Johnson BG, Mitch CH. Zimmerman DM, et al. Among authors: leander jd. J Med Chem. 1993 Oct 1;36(20):2833-41. doi: 10.1021/jm00072a001. J Med Chem. 1993. PMID: 8410998

2

Discovery of a potent, peripherally selective trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidine opioid antagonist for the treatment of gastrointestinal motility disorders.

Zimmerman DM, Gidda JS, Cantrell BE, Schoepp DD, Johnson BG, Leander JD. Zimmerman DM, et al. Among authors: leander jd. J Med Chem. 1994 Jul 22;37(15):2262-5. doi: 10.1021/jm00041a003. J Med Chem. 1994. PMID: 8057274

3

3,4-Dimethyl-4-(3-hydroxyphenyl)piperidines: opioid antagonists with potent anorectant activity.

Mitch CH, Leander JD, Mendelsohn LG, Shaw WN, Wong DT, Cantrell BE, Johnson BG, Reel JK, Snoddy JD, Takemori AE, et al. Mitch CH, et al. Among authors: leander jd. J Med Chem. 1993 Oct 1;36(20):2842-50. doi: 10.1021/jm00072a002. J Med Chem. 1993. PMID: 8410999

4

Selective opioid receptor agonists and antagonists: research tools and potential therapeutic agents.

Zimmerman DM, Leander JD. Zimmerman DM, et al. Among authors: leander jd. J Med Chem. 1990 Mar;33(3):895-902. doi: 10.1021/jm00165a002. J Med Chem. 1990. PMID: 2155322 Review. No abstract available.

5

Opioid antagonists: structure activity relationships.

Zimmerman DM, Leander JD. Zimmerman DM, et al. Among authors: leander jd. NIDA Res Monogr. 1990;96:50-60. NIDA Res Monogr. 1990. PMID: 2172827 Review. No abstract available.

6

Effect of phenylpiperidine opioid antagonists on food consumption and weight gain of the obese Zucker rat.

Shaw WN, Mitch CH, Leander JD, Zimmerman DM. Shaw WN, et al. Among authors: leander jd. J Pharmacol Exp Ther. 1990 Apr;253(1):85-9. J Pharmacol Exp Ther. 1990. PMID: 2329525

7

Synthesis and analgesic properties of N-substituted trans-4a-aryldecahydroisoquinolines.

Zimmerman DM, Cantrell BE, Swartzendruber JK, Jones ND, Mendelsohn LG, Leander JD, Nickander RC. Zimmerman DM, et al. Among authors: leander jd. J Med Chem. 1988 Mar;31(3):555-60. doi: 10.1021/jm00398a011. J Med Chem. 1988. PMID: 2831363

8

Opioid antinociceptive effects of delta-receptor antagonists.

Leander JD, Gesellchen PD, Mendelsohn LG. Leander JD, et al. Pharmacol Biochem Behav. 1988 Feb;29(2):351-5. doi: 10.1016/0091-3057(88)90168-2. Pharmacol Biochem Behav. 1988. PMID: 2834753

9

The effect of the opioid antagonist LY255582 on body weight of the obese Zucker rat.

Shaw WN, Mitch CH, Leander JD, Mendelsohn LG, Zimmerman DM. Shaw WN, et al. Among authors: leander jd. Int J Obes. 1991 Jun;15(6):387-95. Int J Obes. 1991. PMID: 1653188

10

Anticonvulsant effects of phencyclidine-like drugs: relation to N-methyl-D-aspartic acid antagonism.

Leander JD, Rathbun RC, Zimmerman DM. Leander JD, et al. Brain Res. 1988 Jun 28;454(1-2):368-72. doi: 10.1016/0006-8993(88)90839-6. Brain Res. 1988. PMID: 2841999

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