Grimes HL - Search Results

1

Progression of interleukin-2 (IL-2)-dependent rat T cell lymphoma lines to IL-2-independent growth following activation of a gene (Gfi-1) encoding a novel zinc finger protein.

Gilks CB, Bear SE, Grimes HL, Tsichlis PN. Gilks CB, et al. Among authors: grimes hl. Mol Cell Biol. 1993 Mar;13(3):1759-68. doi: 10.1128/mcb.13.3.1759-1768.1993. Mol Cell Biol. 1993. PMID: 8441411 Free PMC article.

2

Chromosomal localization of a gene, GF1, encoding a novel zinc finger protein reveals a new syntenic region between man and rodents.

Bell DW, Taguchi T, Jenkins NA, Gilbert DJ, Copeland NG, Gilks CB, Zweidler-McKay P, Grimes HL, Tsichlis PN, Testa JR. Bell DW, et al. Among authors: grimes hl. Cytogenet Cell Genet. 1995;70(3-4):263-7. doi: 10.1159/000134048. Cytogenet Cell Genet. 1995. PMID: 7789186

3

Gfi-1 encodes a nuclear zinc finger protein that binds DNA and functions as a transcriptional repressor.

Zweidler-Mckay PA, Grimes HL, Flubacher MM, Tsichlis PN. Zweidler-Mckay PA, et al. Among authors: grimes hl. Mol Cell Biol. 1996 Aug;16(8):4024-34. doi: 10.1128/MCB.16.8.4024. Mol Cell Biol. 1996. PMID: 8754800 Free PMC article.

4

The Gfi-1 proto-oncoprotein contains a novel transcriptional repressor domain, SNAG, and inhibits G1 arrest induced by interleukin-2 withdrawal.

Grimes HL, Chan TO, Zweidler-McKay PA, Tong B, Tsichlis PN. Grimes HL, et al. Mol Cell Biol. 1996 Nov;16(11):6263-72. doi: 10.1128/MCB.16.11.6263. Mol Cell Biol. 1996. PMID: 8887656 Free PMC article.

5

The Gfi-1 protooncoprotein represses Bax expression and inhibits T-cell death.

Grimes HL, Gilks CB, Chan TO, Porter S, Tsichlis PN. Grimes HL, et al. Proc Natl Acad Sci U S A. 1996 Dec 10;93(25):14569-73. doi: 10.1073/pnas.93.25.14569. Proc Natl Acad Sci U S A. 1996. PMID: 8962093 Free PMC article.

6

Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase.

Ahmed NN, Grimes HL, Bellacosa A, Chan TO, Tsichlis PN. Ahmed NN, et al. Among authors: grimes hl. Proc Natl Acad Sci U S A. 1997 Apr 15;94(8):3627-32. doi: 10.1073/pnas.94.8.3627. Proc Natl Acad Sci U S A. 1997. PMID: 9108028 Free PMC article.

7

The Gfi-1B proto-oncoprotein represses p21WAF1 and inhibits myeloid cell differentiation.

Tong B, Grimes HL, Yang TY, Bear SE, Qin Z, Du K, El-Deiry WS, Tsichlis PN. Tong B, et al. Among authors: grimes hl. Mol Cell Biol. 1998 May;18(5):2462-73. doi: 10.1128/MCB.18.5.2462. Mol Cell Biol. 1998. PMID: 9566867 Free PMC article.

8

Cyclin D expression is controlled post-transcriptionally via a phosphatidylinositol 3-kinase/Akt-dependent pathway.

Muise-Helmericks RC, Grimes HL, Bellacosa A, Malstrom SE, Tsichlis PN, Rosen N. Muise-Helmericks RC, et al. Among authors: grimes hl. J Biol Chem. 1998 Nov 6;273(45):29864-72. doi: 10.1074/jbc.273.45.29864. J Biol Chem. 1998. PMID: 9792703 Free article.

9

Growth factor independence-1B expression leads to defects in T cell activation, IL-7 receptor alpha expression, and T cell lineage commitment.

Doan LL, Kitay MK, Yu Q, Singer A, Herblot S, Hoang T, Bear SE, Morse HC 3rd, Tsichlis PN, Grimes HL. Doan LL, et al. Among authors: grimes hl. J Immunol. 2003 Mar 1;170(5):2356-66. doi: 10.4049/jimmunol.170.5.2356. J Immunol. 2003. PMID: 12594258

10

Targeted transcriptional repression of Gfi1 by GFI1 and GFI1B in lymphoid cells.

Doan LL, Porter SD, Duan Z, Flubacher MM, Montoya D, Tsichlis PN, Horwitz M, Gilks CB, Grimes HL. Doan LL, et al. Among authors: grimes hl. Nucleic Acids Res. 2004 May 6;32(8):2508-19. doi: 10.1093/nar/gkh570. Print 2004. Nucleic Acids Res. 2004. PMID: 15131254 Free PMC article.

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