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Trp221 is involved in the protective effect of elongation factor eEF-2 on the ricin/alpha-sarcin site of the ribosome.
Guillot D, Lavergne JP, Reboud JP. Guillot D, et al. J Biol Chem. 1993 Dec 15;268(35):26082-4. J Biol Chem. 1993. PMID: 8253723 Free article.
Elongation factor eEF-2 treated by N-bromosuccinimide under conditions which oxidize 2 Trp residues (Trp343 and Trp221) is inactivated in ribosome-dependent GTP hydrolysis and polyphenylalanine synthesis, and inactivation correlates with the specific oxidation of Trp221 (Guill
Elongation factor eEF-2 treated by N-bromosuccinimide under conditions which oxidize 2 Trp residues (Trp343 and Trp221) is inactivated in ri …
21 results