ter Laak AM - Search Results

1

Modelling and mutation studies on the histamine H1-receptor agonist binding site reveal different binding modes for H1-agonists: Asp116 (TM3) has a constitutive role in receptor stimulation.

ter Laak AM, Timmerman H, Leurs R, Nederkoorn PH, Smit MJ, Donné-Op den Kelder GM. ter Laak AM, et al. J Comput Aided Mol Des. 1995 Aug;9(4):319-30. doi: 10.1007/BF00125173. J Comput Aided Mol Des. 1995. PMID: 8523041

2

The histamine H1-receptor antagonist binding site. A stereoselective pharmacophoric model based upon (semi-)rigid H1-antagonists and including a known interaction site on the receptor.

ter Laak AM, Venhorst J, Donné-Op den Kelder GM, Timmerman H. ter Laak AM, et al. J Med Chem. 1995 Aug 18;38(17):3351-60. doi: 10.1021/jm00017a019. J Med Chem. 1995. PMID: 7650688

3

Lysine200 located in the fifth transmembrane domain of the histamine H1 receptor interacts with histamine but not with all H1 agonists.

Leurs R, Smit MJ, Meeder R, Ter Laak AM, Timmerman H. Leurs R, et al. Among authors: ter laak am. Biochem Biophys Res Commun. 1995 Sep 5;214(1):110-7. doi: 10.1006/bbrc.1995.2263. Biochem Biophys Res Commun. 1995. PMID: 7669031

4

Is there a difference in the affinity of histamine H1 receptor antagonists for CNS and peripheral receptors? An in vitro study.

Ter Laak AM, Donné-Op den Kelder GM, Bast A, Timmerman H. Ter Laak AM, et al. Eur J Pharmacol. 1993 Mar 2;232(2-3):199-205. doi: 10.1016/0014-2999(93)90774-c. Eur J Pharmacol. 1993. PMID: 8096817

5

Site-directed mutagenesis of the histamine H1-receptor reveals a selective interaction of asparagine207 with subclasses of H1-receptor agonists.

Leurs R, Smit MJ, Tensen CP, Ter Laak AM, Timmerman H. Leurs R, et al. Among authors: ter laak am. Biochem Biophys Res Commun. 1994 May 30;201(1):295-301. doi: 10.1006/bbrc.1994.1701. Biochem Biophys Res Commun. 1994. PMID: 8198587

6

Optically active analogues of ebastine: synthesis and effect of chirality on their antihistaminic and antimuscarinic activity.

Zhang MQ, Walczynski K, Ter Laak AM, Timmerman H. Zhang MQ, et al. Among authors: ter laak am. Chirality. 1994;6(8):631-41. doi: 10.1002/chir.530060806. Chirality. 1994. PMID: 7857774

7

Modeling and molecular dynamics of glutamine transaminase K/cysteine conjugate beta-lyase.

Venhorst J, ter Laak AM, Meijer M, van de Wetering I, Commandeur JN, Rooseboom M, Vermeulen NP. Venhorst J, et al. Among authors: ter laak am. J Mol Graph Model. 2003 Sep;22(1):55-70. doi: 10.1016/S1093-3263(03)00136-0. J Mol Graph Model. 2003. PMID: 12798391

8

Molecular modelling of asperlicin derived cholecystokinin A receptor antagonists.

Van der Bent A, Ter Laak AM, IJzerman AP, Soudijn W. Van der Bent A, et al. Among authors: ter laak am. Eur J Pharmacol. 1992 Aug 3;226(4):327-34. doi: 10.1016/0922-4106(92)90050-6. Eur J Pharmacol. 1992. PMID: 1397061

9

Prediction of ligand binding affinity and orientation of xenoestrogens to the estrogen receptor by molecular dynamics simulations and the linear interaction energy method.

van Lipzig MM, ter Laak AM, Jongejan A, Vermeulen NP, Wamelink M, Geerke D, Meerman JH. van Lipzig MM, et al. Among authors: ter laak am. J Med Chem. 2004 Feb 12;47(4):1018-30. doi: 10.1021/jm0309607. J Med Chem. 2004. PMID: 14761204

10

Homology modeling of rat and human cytochrome P450 2D (CYP2D) isoforms and computational rationalization of experimental ligand-binding specificities.

Venhorst J, ter Laak AM, Commandeur JN, Funae Y, Hiroi T, Vermeulen NP. Venhorst J, et al. Among authors: ter laak am. J Med Chem. 2003 Jan 2;46(1):74-86. doi: 10.1021/jm0209578. J Med Chem. 2003. PMID: 12502361

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

37 results

Search Page

Filters