Schoepp DD - Search Results

1

(3SR,4aRS,6SR,8aRS)-6-(1H-tetrazol-5-yl)decahydroisoquinoline-3-carboxylic acid, a novel, competitive, systemically active NMDA and AMPA receptor antagonist.

Ornstein PL, Arnold MB, Allen NK, Leander JD, Tizzano JP, Lodge D, Schoepp DD. Ornstein PL, et al. Among authors: schoepp dd. J Med Chem. 1995 Dec 8;38(25):4885-90. doi: 10.1021/jm00025a005. J Med Chem. 1995. PMID: 8523401

2

Synthesis and structure-activity relationship studies of novel 2-diarylethyl substituted (2-carboxycycloprop-1-yl)glycines as high-affinity group II metabotropic glutamate receptor ligands.

Sørensen US, Bleisch TJ, Kingston AE, Wright RA, Johnson BG, Schoepp DD, Ornstein PL. Sørensen US, et al. Among authors: schoepp dd. Bioorg Med Chem. 2003 Jan 17;11(2):197-205. doi: 10.1016/s0968-0896(02)00387-5. Bioorg Med Chem. 2003. PMID: 12470714

3

Discovery of allosteric potentiators for the metabotropic glutamate 2 receptor: synthesis and subtype selectivity of N-(4-(2-methoxyphenoxy)phenyl)-N-(2,2,2- trifluoroethylsulfonyl)pyrid-3-ylmethylamine.

Johnson MP, Baez M, Jagdmann GE Jr, Britton TC, Large TH, Callagaro DO, Tizzano JP, Monn JA, Schoepp DD. Johnson MP, et al. Among authors: schoepp dd. J Med Chem. 2003 Jul 17;46(15):3189-92. doi: 10.1021/jm034015u. J Med Chem. 2003. PMID: 12852748

4

D,L-(tetrazol-5-yl) glycine: a novel and highly potent NMDA receptor agonist.

Schoepp DD, Smith CL, Lodge D, Millar JD, Leander JD, Sacaan AI, Lunn WH. Schoepp DD, et al. Eur J Pharmacol. 1991 Oct 15;203(2):237-43. doi: 10.1016/0014-2999(91)90719-7. Eur J Pharmacol. 1991. PMID: 1686860

5

4-(Tetrazolylalkyl)piperidine-2-carboxylic acids. Potent and selective N-methyl-D-aspartic acid receptor antagonists with a short duration of action.

Ornstein PL, Schoepp DD, Arnold MB, Leander JD, Lodge D, Paschal JW, Elzey T. Ornstein PL, et al. Among authors: schoepp dd. J Med Chem. 1991 Jan;34(1):90-7. doi: 10.1021/jm00105a016. J Med Chem. 1991. PMID: 1825117

6

Neuroprotectant effects of LY274614, a structurally novel systemically active competitive NMDA receptor antagonist.

Schoepp DD, Ornstein PL, Salhoff CR, Leander JD. Schoepp DD, et al. J Neural Transm Gen Sect. 1991;85(2):131-43. doi: 10.1007/BF01244705. J Neural Transm Gen Sect. 1991. PMID: 1834088

7

Pharmacological characterization of LY233053: a structurally novel tetrazole-substituted competitive N-methyl-D-aspartic acid antagonist with a short duration of action.

Schoepp DD, Ornstein PL, Leander JD, Lodge D, Salhoff CR, Zeman S, Zimmerman DM. Schoepp DD, et al. J Pharmacol Exp Ther. 1990 Dec;255(3):1301-8. J Pharmacol Exp Ther. 1990. PMID: 2148188

8

LY233053: a structurally novel, potent and selective competitive N-methyl-D-aspartate receptor antagonist.

Ornstein PL, Schoepp DD, Leander JD, Wong T, Zimmerman DM, Lodge D. Ornstein PL, et al. Among authors: schoepp dd. Prog Clin Biol Res. 1990;361:429-33. Prog Clin Biol Res. 1990. PMID: 2149764 No abstract available.

9

Cyclothiazide acts at a site on the alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor complex that does not recognize competitive or noncompetitive AMPA receptor antagonists.

Desai MA, Burnett JP, Ornstein PL, Schoepp DD. Desai MA, et al. Among authors: schoepp dd. J Pharmacol Exp Ther. 1995 Jan;272(1):38-43. J Pharmacol Exp Ther. 1995. PMID: 7529311

10

Discovery of a potent, peripherally selective trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidine opioid antagonist for the treatment of gastrointestinal motility disorders.

Zimmerman DM, Gidda JS, Cantrell BE, Schoepp DD, Johnson BG, Leander JD. Zimmerman DM, et al. Among authors: schoepp dd. J Med Chem. 1994 Jul 22;37(15):2262-5. doi: 10.1021/jm00041a003. J Med Chem. 1994. PMID: 8057274

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