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Page 1
CP-123,369: a potent, orally active immunosuppressive agent.
Koch K, Hanson DC, Newborg MF, Cooper K, Fouda HG, Biehl ML, Shepard RM, Donovan CB, Biggers MS, Ramchandani M, et al. Koch K, et al. Among authors: biggers ms. Inflamm Res. 1995 Aug;44 Suppl 2:S183-4. doi: 10.1007/BF01778322. Inflamm Res. 1995. PMID: 8548388 No abstract available.
trans-3-Benzyl-4-hydroxy-7-chromanylbenzoic acid derivatives as antagonists of the leukotriene B4 (LTB4) receptor.
Reiter LA, Koch K, Piscopio AD, Showell HJ, Alpert R, Biggers MS, Chambers RJ, Conklyn MJ, Cooper K, Cortina SR, Dibrino JN, Dominy BW, Farrell CA, Hingorani GP, Martinelli GJ, Ramchandani M, Wright KF. Reiter LA, et al. Among authors: biggers ms. Bioorg Med Chem Lett. 1998 Jul 21;8(14):1781-6. doi: 10.1016/s0960-894x(98)00275-3. Bioorg Med Chem Lett. 1998. PMID: 9873433
(+)-1-(3S,4R)-[3-(4-phenylbenzyl)-4-hydroxychroman-7-yl]cyclopentane carboxylic acid, a highly potent, selective leukotriene B4 antagonist with oral activity in the murine collagen-induced arthritis model.
Koch K, Melvin LS Jr, Reiter LA, Biggers MS, Showell HJ, Griffiths RJ, Pettipher ER, Cheng JB, Milici AJ, Breslow R, et al. Koch K, et al. Among authors: biggers ms. J Med Chem. 1994 Sep 30;37(20):3197-9. doi: 10.1021/jm00046a001. J Med Chem. 1994. PMID: 7932545 No abstract available.
Biarylcarboxylic acids and -amides: inhibition of phosphodiesterase type IV versus [3H]rolipram binding activity and their relationship to emetic behavior in the ferret.
Duplantier AJ, Biggers MS, Chambers RJ, Cheng JB, Cooper K, Damon DB, Eggler JF, Kraus KG, Marfat A, Masamune H, Pillar JS, Shirley JT, Umland JP, Watson JW. Duplantier AJ, et al. Among authors: biggers ms. J Med Chem. 1996 Jan 5;39(1):120-5. doi: 10.1021/jm9505066. J Med Chem. 1996. PMID: 8568798