Yamazaki H - Search Results

1

Roles of cytochrome b5 in the oxidation of testosterone and nifedipine by recombinant cytochrome P450 3A4 and by human liver microsomes.

Yamazaki H, Nakano M, Imai Y, Ueng YF, Guengerich FP, Shimada T. Yamazaki H, et al. Arch Biochem Biophys. 1996 Jan 15;325(2):174-82. doi: 10.1006/abbi.1996.0022. Arch Biochem Biophys. 1996. PMID: 8561495

2

Bufuralol hydroxylation by cytochrome P450 2D6 and 1A2 enzymes in human liver microsomes.

Yamazaki H, Guo Z, Persmark M, Mimura M, Inoue K, Guengerich FP, Shimada T. Yamazaki H, et al. Mol Pharmacol. 1994 Sep;46(3):568-77. Mol Pharmacol. 1994. PMID: 7935340

3

Catalytic roles of rat and human cytochrome P450 2A enzymes in testosterone 7 alpha- and coumarin 7-hydroxylations.

Yamazaki H, Mimura M, Sugahara C, Shimada T. Yamazaki H, et al. Biochem Pharmacol. 1994 Oct 7;48(7):1524-7. doi: 10.1016/0006-2952(94)90579-7. Biochem Pharmacol. 1994. PMID: 7945454

4

Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

Shimada T, Yamazaki H, Mimura M, Inui Y, Guengerich FP. Shimada T, et al. Among authors: yamazaki h. J Pharmacol Exp Ther. 1994 Jul;270(1):414-23. J Pharmacol Exp Ther. 1994. PMID: 8035341

5

Activation of trans-1,2-dihydro-1,2-dihydroxy-6-aminochrysene to genotoxic metabolites by rat and human cytochromes P450.

Yamazaki H, Mimura M, Oda Y, Gonzalez FJ, el-Bayoumy K, Chae YH, Guengerich FP, Shimada T. Yamazaki H, et al. Carcinogenesis. 1994 Mar;15(3):465-70. doi: 10.1093/carcin/15.3.465. Carcinogenesis. 1994. PMID: 8118930

6

Roles of different forms of cytochrome P450 in the activation of the promutagen 6-aminochrysene to genotoxic metabolites in human liver microsomes.

Yamazaki H, Mimura M, Oda Y, Inui Y, Shiraga T, Iwasaki K, Guengerich FP, Shimada T. Yamazaki H, et al. Carcinogenesis. 1993 Jul;14(7):1271-8. doi: 10.1093/carcin/14.7.1271. Carcinogenesis. 1993. PMID: 8330339

We reported previously that the potent mutagen 6-aminochrysene is catalyzed principally by rat liver microsomal P4501A and P4502B enzymes to reactive metabolites that induce umu gene expression in O-acetyltransferase-over-expressing strain Salmonella typhimurium NM2009; the propo …

We reported previously that the potent mutagen 6-aminochrysene is catalyzed principally by rat liver microsomal P4501A and P4502B enzymes to …

7

7-Ethoxycoumarin O-deethylation catalyzed by cytochromes P450 1A2 and 2E1 in human liver microsomes.

Yamazaki H, Inoue K, Mimura M, Oda Y, Guengerich FP, Shimada T. Yamazaki H, et al. Biochem Pharmacol. 1996 Feb 9;51(3):313-9. doi: 10.1016/0006-2952(95)02178-7. Biochem Pharmacol. 1996. PMID: 8573198

8

Recombinant human cytochrome P450 1A2 and an N-terminal-truncated form: construction, purification, aggregation properties, and interactions with flavodoxin, ferredoxin, and NADPH-cytochrome P450 reductase.

Dong MS, Yamazaki H, Guo Z, Guengerich FP. Dong MS, et al. Among authors: yamazaki h. Arch Biochem Biophys. 1996 Mar 1;327(1):11-9. doi: 10.1006/abbi.1996.0086. Arch Biochem Biophys. 1996. PMID: 8615680

9

Requirements for cytochrome b5 in the oxidation of 7-ethoxycoumarin, chlorzoxazone, aniline, and N-nitrosodimethylamine by recombinant cytochrome P450 2E1 and by human liver microsomes.

Yamazaki H, Nakano M, Gillam EM, Bell LC, Guengerich FP, Shimada T. Yamazaki H, et al. Biochem Pharmacol. 1996 Jul 26;52(2):301-9. doi: 10.1016/0006-2952(96)00208-0. Biochem Pharmacol. 1996. PMID: 8694855

10

Characterization of microsomal cytochrome P450 enzymes involved in the oxidation of xenobiotic chemicals in human fetal liver and adult lungs.

Shimada T, Yamazaki H, Mimura M, Wakamiya N, Ueng YF, Guengerich FP, Inui Y. Shimada T, et al. Among authors: yamazaki h. Drug Metab Dispos. 1996 May;24(5):515-22. Drug Metab Dispos. 1996. PMID: 8723730

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