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Transfer of a constitutive viral promoter-cystic fibrosis transmembrane conductance regulator cDNA to human epithelial cells conveys resistance to down-regulation of cAMP-regulated Cl- secretion in the presence of inflammatory stimuli.
Kobayashi N, Rosenthal ER, Yoshimura K, Crystal RG. Kobayashi N, et al. Among authors: crystal rg. Nucleic Acids Res. 1994 Oct 25;22(21):4470-6. doi: 10.1093/nar/22.21.4470. Nucleic Acids Res. 1994. PMID: 7526342 Free PMC article.
Extensive posttranscriptional deletion of the coding sequences for part of nucleotide-binding fold 1 in respiratory epithelial mRNA transcripts of the cystic fibrosis transmembrane conductance regulator gene is not associated with the clinical manifestations of cystic fibrosis.
Chu CS, Trapnell BC, Curristin SM, Cutting GR, Crystal RG. Chu CS, et al. Among authors: crystal rg. J Clin Invest. 1992 Sep;90(3):785-90. doi: 10.1172/JCI115952. J Clin Invest. 1992. PMID: 1381723 Free PMC article.
912 results