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Amino-terminal protein-protein interaction motif (POZ-domain) is responsible for activities of the promyelocytic leukemia zinc finger-retinoic acid receptor-alpha fusion protein.
Dong S, Zhu J, Reid A, Strutt P, Guidez F, Zhong HJ, Wang ZY, Licht J, Waxman S, Chomienne C, Chen Z, Zelent A, Chen SJ. Dong S, et al. Among authors: chen z, chen sj. Proc Natl Acad Sci U S A. 1996 Apr 16;93(8):3624-9. doi: 10.1073/pnas.93.8.3624. Proc Natl Acad Sci U S A. 1996. PMID: 8622986 Free PMC article.
RARA and PML genes in acute promyelocytic leukemia.
Chen Z, Chen SJ. Chen Z, et al. Among authors: chen sj. Leuk Lymphoma. 1992 Nov;8(4-5):253-60. doi: 10.3109/10428199209051004. Leuk Lymphoma. 1992. PMID: 1337847 Review.
PLZF-RAR alpha fusion proteins generated from the variant t(11;17)(q23;q21) translocation in acute promyelocytic leukemia inhibit ligand-dependent transactivation of wild-type retinoic acid receptors.
Chen Z, Guidez F, Rousselot P, Agadir A, Chen SJ, Wang ZY, Degos L, Zelent A, Waxman S, Chomienne C. Chen Z, et al. Among authors: chen sj. Proc Natl Acad Sci U S A. 1994 Feb 1;91(3):1178-82. doi: 10.1073/pnas.91.3.1178. Proc Natl Acad Sci U S A. 1994. PMID: 8302850 Free PMC article.
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