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Amino-terminal protein-protein interaction motif (POZ-domain) is responsible for activities of the promyelocytic leukemia zinc finger-retinoic acid receptor-alpha fusion protein.
Dong S, Zhu J, Reid A, Strutt P, Guidez F, Zhong HJ, Wang ZY, Licht J, Waxman S, Chomienne C, Chen Z, Zelent A, Chen SJ. Dong S, et al. Among authors: guidez f. Proc Natl Acad Sci U S A. 1996 Apr 16;93(8):3624-9. doi: 10.1073/pnas.93.8.3624. Proc Natl Acad Sci U S A. 1996. PMID: 8622986 Free PMC article.
PLZF-RAR alpha fusion proteins generated from the variant t(11;17)(q23;q21) translocation in acute promyelocytic leukemia inhibit ligand-dependent transactivation of wild-type retinoic acid receptors.
Chen Z, Guidez F, Rousselot P, Agadir A, Chen SJ, Wang ZY, Degos L, Zelent A, Waxman S, Chomienne C. Chen Z, et al. Among authors: guidez f. Proc Natl Acad Sci U S A. 1994 Feb 1;91(3):1178-82. doi: 10.1073/pnas.91.3.1178. Proc Natl Acad Sci U S A. 1994. PMID: 8302850 Free PMC article.
Benzodithiophenes potentiate differentiation of acute promyelocytic leukemia cells by lowering the threshold for ligand-mediated corepressor/coactivator exchange with retinoic acid receptor alpha and enhancing changes in all-trans-retinoic acid-regulated gene expression.
Xu K, Guidez F, Glasow A, Chung D, Petrie K, Stegmaier K, Wang KK, Zhang J, Jing Y, Zelent A, Waxman S. Xu K, et al. Among authors: guidez f. Cancer Res. 2005 Sep 1;65(17):7856-65. doi: 10.1158/0008-5472.CAN-05-1056. Cancer Res. 2005. PMID: 16140955
Role of nuclear receptor corepressors in leukemogenesis.
Guidez F, Zelent A. Guidez F, et al. Curr Top Microbiol Immunol. 2001;254:165-85. doi: 10.1007/978-3-662-10595-5_9. Curr Top Microbiol Immunol. 2001. PMID: 11190573 Review. No abstract available.
54 results