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Somatostatin inhibits PC Cl3 thyroid cell proliferation through the modulation of phosphotyrosine activity. Impairment of the somatostatinergic effects by stable expression of E1A viral oncogene.
Florio T, Scorizello A, Fattore M, D'Alto V, Salzano S, Rossi G, Berlingieri MT, Fusco A, Schettini G. Florio T, et al. Among authors: schettini g. J Biol Chem. 1996 Mar 15;271(11):6129-36. doi: 10.1074/jbc.271.11.6129. J Biol Chem. 1996. PMID: 8626400 Free article.
The expression of the phosphotyrosine phosphatase DEP-1/PTPeta dictates the responsivity of glioma cells to somatostatin inhibition of cell proliferation.
Massa A, Barbieri F, Aiello C, Arena S, Pattarozzi A, Pirani P, Corsaro A, Iuliano R, Fusco A, Zona G, Spaziante R, Florio T, Schettini G. Massa A, et al. Among authors: schettini g. J Biol Chem. 2004 Jul 9;279(28):29004-12. doi: 10.1074/jbc.M403573200. Epub 2004 Apr 30. J Biol Chem. 2004. PMID: 15123617 Free article.
Alpha 1 B, but not alpha 1A, adrenoreceptor activates calcium influx through the stimulation of a tyrosine kinase/phosphotyrosine phosphatase pathway, following noradrenaline-induced emptying of IP3 sensitive calcium stores, in PC Cl3 rat thyroid cell line.
Meucci O, Scorziello A, Avallone A, Florio T, D'Alto V, Fattore M, Schettini G. Meucci O, et al. Among authors: schettini g. Biochem Biophys Res Commun. 1995 Apr 17;209(2):630-8. doi: 10.1006/bbrc.1995.1546. Biochem Biophys Res Commun. 1995. PMID: 7537494
Alpha 1A- and alpha 1B-adrenergic receptors mediate the effect of norepinephrine on cytosolic calcium levels in rat PC C13 thyroid cells: thyrotropin modulation of alpha 1B-linked response via a adenosine 3',5'-monophosphate-protein kinase-A-dependent pathway.
Meucci O, Scorziello A, Avallone A, Ventra C, Grimaldi M, Berlingieri MT, Fusco A, Schettini G. Meucci O, et al. Among authors: schettini g. Endocrinology. 1994 Jan;134(1):424-31. doi: 10.1210/endo.134.1.7903935. Endocrinology. 1994. PMID: 7903935
243 results