Wigginton JM - Search Results

1

Interleukin 12 primes macrophages for nitric oxide production in vivo and restores depressed nitric oxide production by macrophages from tumor-bearing mice: implications for the antitumor activity of interleukin 12 and/or interleukin 2.

Wigginton JM, Kuhns DB, Back TC, Brunda MJ, Wiltrout RH, Cox GW. Wigginton JM, et al. Cancer Res. 1996 Mar 1;56(5):1131-6. Cancer Res. 1996. PMID: 8640772

2

Antitumor activity of interleukin 12 in preclinical models.

Brunda MJ, Luistro L, Rumennik L, Wright RB, Dvorozniak M, Aglione A, Wigginton JM, Wiltrout RH, Hendrzak JA, Palleroni AV. Brunda MJ, et al. Among authors: wigginton jm. Cancer Chemother Pharmacol. 1996;38 Suppl:S16-21. doi: 10.1007/s002800051031. Cancer Chemother Pharmacol. 1996. PMID: 8765410 Review.

3

Administration of interleukin 12 with pulse interleukin 2 and the rapid and complete eradication of murine renal carcinoma.

Wigginton JM, Komschlies KL, Back TC, Franco JL, Brunda MJ, Wiltrout RH. Wigginton JM, et al. J Natl Cancer Inst. 1996 Jan 3;88(1):38-43. doi: 10.1093/jnci/88.1.38. J Natl Cancer Inst. 1996. PMID: 8847724

4

Evaluation of the antitumor activity of the interleukin-12/pulse interleukin-2 combination.

Wigginton JM, Komschlies KL, Green JE, Cox GW, Jorcyk CL, Back TC, Franco JL, Brunda MJ, Wiltrout RH. Wigginton JM, et al. Ann N Y Acad Sci. 1996 Oct 31;795:434-9. doi: 10.1111/j.1749-6632.1996.tb52714.x. Ann N Y Acad Sci. 1996. PMID: 8958976 No abstract available.

5

Induction of transplantable mouse renal cell cancers by streptozotocin: in vivo growth, metastases, and angiogenic phenotype.

Gruys ME, Back TC, Subleski J, Wiltrout TA, Lee JK, Schmidt L, Watanabe M, Stanyon R, Ward JM, Wigginton JM, Wiltrout RH. Gruys ME, et al. Among authors: wigginton jm. Cancer Res. 2001 Aug 15;61(16):6255-63. Cancer Res. 2001. PMID: 11507080

6

Regulation of local host-mediated anti-tumor mechanisms by cytokines: direct and indirect effects on leukocyte recruitment and angiogenesis.

Watanabe M, McCormick KL, Volker K, Ortaldo JR, Wigginton JM, Brunda MJ, Wiltrout RH, Fogler WE. Watanabe M, et al. Among authors: wigginton jm. Am J Pathol. 1997 May;150(5):1869-80. Am J Pathol. 1997. PMID: 9137109 Free PMC article.

7

Molecular mechanisms of immune-mediated lysis of murine renal cancer: differential contributions of perforin-dependent versus Fas-mediated pathways in lysis by NK and T cells.

Sayers TJ, Brooks AD, Lee JK, Fenton RG, Komschlies KL, Wigginton JM, Winkler-Pickett R, Wiltrout RH. Sayers TJ, et al. Among authors: wigginton jm. J Immunol. 1998 Oct 15;161(8):3957-65. J Immunol. 1998. PMID: 9780164

8

Recruitment of hepatic NK cells by IL-12 is dependent on IFN-gamma and VCAM-1 and is rapidly down-regulated by a mechanism involving T cells and expression of Fas.

Fogler WE, Volker K, Watanabe M, Wigginton JM, Roessler P, Brunda MJ, Ortaldo JR, Wiltrout RH. Fogler WE, et al. Among authors: wigginton jm. J Immunol. 1998 Dec 1;161(11):6014-21. J Immunol. 1998. PMID: 9834083

9

Intradermal delivery of IL-12 naked DNA induces systemic NK cell activation and Th1 response in vivo that is independent of endogenous IL-12 production.

Watanabe M, Fenton RG, Wigginton JM, McCormick KL, Volker KM, Fogler WE, Roessler PG, Wiltrout RH. Watanabe M, et al. Among authors: wigginton jm. J Immunol. 1999 Aug 15;163(4):1943-50. J Immunol. 1999. PMID: 10438930

10

IFN-gamma-dependent delay of in vivo tumor progression by Fas overexpression on murine renal cancer cells.

Lee JK, Sayers TJ, Brooks AD, Back TC, Young HA, Komschlies KL, Wigginton JM, Wiltrout RH. Lee JK, et al. Among authors: wigginton jm. J Immunol. 2000 Jan 1;164(1):231-9. doi: 10.4049/jimmunol.164.1.231. J Immunol. 2000. PMID: 10605016

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