Marwood R - Search Results

1

3-((4-(4-Chlorophenyl)piperazin-1-yl)-methyl)-1H-pyrrolo-2,3-b-pyridine: an antagonist with high affinity and selectivity for the human dopamine D4 receptor.

Kulagowski JJ, Broughton HB, Curtis NR, Mawer IM, Ridgill MP, Baker R, Emms F, Freedman SB, Marwood R, Patel S, Patel S, Ragan CI, Leeson PD. Kulagowski JJ, et al. Among authors: marwood r. J Med Chem. 1996 May 10;39(10):1941-2. doi: 10.1021/jm9600712. J Med Chem. 1996. PMID: 8642550 No abstract available.

2

5-(4-Chlorophenyl)-4-methyl-3-(1-(2-phenylethyl)piperidin-4-yl)isoxazole: a potent, selective antagonist at human cloned dopamine D4 receptors.

Rowley M, Broughton HB, Collins I, Baker R, Emms F, Marwood R, Patel S, Patel S, Ragan CI, Freedman SB, Leeson PD. Rowley M, et al. Among authors: marwood r. J Med Chem. 1996 May 10;39(10):1943-5. doi: 10.1021/jm960072u. J Med Chem. 1996. PMID: 8642551 No abstract available.

3

Identification and pharmacological characterization of [125I]L-750,667, a novel radioligand for the dopamine D4 receptor.

Patel S, Patel S, Marwood R, Emms F, Marston D, Leeson PD, Curtis NR, Kulagowski JJ, Freedman SB. Patel S, et al. Among authors: marwood r. Mol Pharmacol. 1996 Dec;50(6):1658-64. Mol Pharmacol. 1996. PMID: 8967990

4

4-Heterocyclylpiperidines as selective high-affinity ligands at the human dopamine D4 receptor.

Rowley M, Collins I, Broughton HB, Davey WB, Baker R, Emms F, Marwood R, Patel S, Patel S, Ragan CI, Freedman SB, Ball R, Leeson PD. Rowley M, et al. Among authors: marwood r. J Med Chem. 1997 Jul 18;40(15):2374-85. doi: 10.1021/jm970111h. J Med Chem. 1997. PMID: 9240352

5

Biological profile of L-745,870, a selective antagonist with high affinity for the dopamine D4 receptor.

Patel S, Freedman S, Chapman KL, Emms F, Fletcher AE, Knowles M, Marwood R, Mcallister G, Myers J, Curtis N, Kulagowski JJ, Leeson PD, Ridgill M, Graham M, Matheson S, Rathbone D, Watt AP, Bristow LJ, Rupniak NM, Baskin E, Lynch JJ, Ragan CI. Patel S, et al. Among authors: marwood r. J Pharmacol Exp Ther. 1997 Nov;283(2):636-47. J Pharmacol Exp Ther. 1997. PMID: 9353380

6

Binding of 2,4-disubstituted morpholines at human D4 dopamine receptors.

Showell GA, Emms F, Marwood R, O'Connor D, Patel S, Leeson PD. Showell GA, et al. Among authors: marwood r. Bioorg Med Chem. 1998 Jan;6(1):1-8. doi: 10.1016/s0968-0896(97)00176-4. Bioorg Med Chem. 1998. PMID: 9502100

7

3-(1-piperazinyl)-4,5-dihydro-1H-benzo[g]indazoles: high affinity ligands for the human dopamine D4 receptor with improved selectivity over ion channels.

Collins I, Rowley M, Davey WB, Emms F, Marwood R, Patel S, Patel S, Fletcher A, Ragan IC, Leeson PD, Scott AL, Broten T. Collins I, et al. Among authors: marwood r. Bioorg Med Chem. 1998 Jun;6(6):743-53. doi: 10.1016/s0968-0896(98)00028-5. Bioorg Med Chem. 1998. PMID: 9681140

8

Substituted pyrazoles as novel selective ligands for the human dopamine D4 receptor.

Bourrain S, Collins I, Neduvelil JG, Rowley M, Leeson PD, Patel S, Patel S, Emms F, Marwood R, Chapman KL, Fletcher AE, Showell GA. Bourrain S, et al. Among authors: marwood r. Bioorg Med Chem. 1998 Oct;6(10):1731-43. doi: 10.1016/s0968-0896(98)00134-5. Bioorg Med Chem. 1998. PMID: 9839003

9

4-N-linked-heterocyclic piperidine derivatives with high affinity and selectivity for human dopamine D4 receptors.

Moore KW, Bonner K, Jones EA, Emms F, Leeson PD, Marwood R, Patel S, Patel S, Rowley M, Thomas S, Carling RW. Moore KW, et al. Among authors: marwood r. Bioorg Med Chem Lett. 1999 May 3;9(9):1285-90. doi: 10.1016/s0960-894x(99)00169-9. Bioorg Med Chem Lett. 1999. PMID: 10340615

10

1-(3-Cyanobenzylpiperidin-4-yl)-5-methyl-4-phenyl-1, 3-dihydroimidazol-2-one: a selective high-affinity antagonist for the human dopamine D(4) receptor with excellent selectivity over ion channels.

Carling RW, Moore KW, Moyes CR, Jones EA, Bonner K, Emms F, Marwood R, Patel S, Patel S, Fletcher AE, Beer M, Sohal B, Pike A, Leeson PD. Carling RW, et al. Among authors: marwood r. J Med Chem. 1999 Jul 15;42(14):2706-15. doi: 10.1021/jm991029k. J Med Chem. 1999. PMID: 10411491

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