Biggs PJ - Search Results

1

The cylindromatosis gene (cyld1) on chromosome 16q may be the only tumour suppressor gene involved in the development of cylindromas.

Biggs PJ, Chapman P, Lakhani SR, Burn J, Stratton MR. Biggs PJ, et al. Oncogene. 1996 Mar 21;12(6):1375-7. Oncogene. 1996. PMID: 8649842

2

Familial cylindromatosis (turban tumour syndrome) gene localised to chromosome 16q12-q13: evidence for its role as a tumour suppressor gene.

Biggs PJ, Wooster R, Ford D, Chapman P, Mangion J, Quirk Y, Easton DF, Burn J, Stratton MR. Biggs PJ, et al. Nat Genet. 1995 Dec;11(4):441-3. doi: 10.1038/ng1295-441. Nat Genet. 1995. PMID: 7493027

3

Identification of the familial cylindromatosis tumour-suppressor gene.

Bignell GR, Warren W, Seal S, Takahashi M, Rapley E, Barfoot R, Green H, Brown C, Biggs PJ, Lakhani SR, Jones C, Hansen J, Blair E, Hofmann B, Siebert R, Turner G, Evans DG, Schrander-Stumpel C, Beemer FA, van Den Ouweland A, Halley D, Delpech B, Cleveland MG, Leigh I, Leisti J, Rasmussen S. Bignell GR, et al. Among authors: biggs pj. Nat Genet. 2000 Jun;25(2):160-5. doi: 10.1038/76006. Nat Genet. 2000. PMID: 10835629

4

Linkage and LOH studies in 19 cylindromatosis families show no evidence of genetic heterogeneity and refine the CYLD locus on chromosome 16q12-q13.

Takahashi M, Rapley E, Biggs PJ, Lakhani SR, Cooke D, Hansen J, Blair E, Hofmann B, Siebert R, Turner G, Evans DG, Schrander-Stumpel C, Beemer FA, van Vloten WA, Breuning MH, van den Ouweland A, Halley D, Delpech B, Cleveland M, Leigh I, Chapman P, Burn J, Hohl D, Görög JP, Seal S, Mangion J. Takahashi M, et al. Among authors: biggs pj. Hum Genet. 2000 Jan;106(1):58-65. doi: 10.1007/s004399900227. Hum Genet. 2000. PMID: 10982183

5

Mutations in the p53 gene in schistosomal bladder cancer: a study of 92 tumours from Egyptian patients and a comparison between mutational spectra from schistosomal and non-schistosomal urothelial tumours.

Warren W, Biggs PJ, el-Baz M, Ghoneim MA, Stratton MR, Venitt S. Warren W, et al. Among authors: biggs pj. Carcinogenesis. 1995 May;16(5):1181-9. doi: 10.1093/carcin/16.5.1181. Carcinogenesis. 1995. PMID: 7767983

6

Does a genotoxic carcinogen contribute to human breast cancer? The value of mutational spectra in unravelling the aetiology of cancer.

Biggs PJ, Warren W, Venitt S, Stratton MR. Biggs PJ, et al. Mutagenesis. 1993 Jul;8(4):275-83. doi: 10.1093/mutage/8.4.275. Mutagenesis. 1993. PMID: 8377645 Review.

7

Familial nontoxic multinodular thyroid goiter locus maps to chromosome 14q but does not account for familial nonmedullary thyroid cancer.

Bignell GR, Canzian F, Shayeghi M, Stark M, Shugart YY, Biggs P, Mangion J, Hamoudi R, Rosenblatt J, Buu P, Sun S, Stoffer SS, Goldgar DE, Romeo G, Houlston RS, Narod SA, Stratton MR, Foulkes WD. Bignell GR, et al. Am J Hum Genet. 1997 Nov;61(5):1123-30. doi: 10.1086/301610. Am J Hum Genet. 1997. PMID: 9345104 Free PMC article.

8

Localization to Xq27 of a susceptibility gene for testicular germ-cell tumours.

Rapley EA, Crockford GP, Teare D, Biggs P, Seal S, Barfoot R, Edwards S, Hamoudi R, Heimdal K, Fossâ SD, Tucker K, Donald J, Collins F, Friedlander M, Hogg D, Goss P, Heidenreich A, Ormiston W, Daly PA, Forman D, Oliver TD, Leahy M, Huddart R, Cooper CS, Bodmer JG, Easton DF, Stratton MR, Bishop DT. Rapley EA, et al. Nat Genet. 2000 Feb;24(2):197-200. doi: 10.1038/72877. Nat Genet. 2000. PMID: 10655070

9

Allelic phasing of a mouse chromosome 11 deficiency influences p53 tumorigenicity.

Biggs PJ, Vogel H, Sage M, Martin LA, Donehower LA, Bradley A. Biggs PJ, et al. Oncogene. 2003 May 22;22(21):3288-96. doi: 10.1038/sj.onc.1206384. Oncogene. 2003. PMID: 12761499

10

Familial testicular cancer: lack of evidence for trinucleotide repeat expansions and association with PKD1 in one family.

Teh BT, Linblad K, Nord B, Kytölä S, Schalling M, Larsson C, Rapley E, Biggs P, Huddart R, Stratton M. Teh BT, et al. J Med Genet. 1999 Apr;36(4):348-9. J Med Genet. 1999. PMID: 10227410 Free PMC article. No abstract available.

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